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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177898</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177904" alias="SHAH_H000019_T07_04_DLP01-A98179A-R08-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177904</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23177905</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177906</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23177907</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23177908</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177909</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23177913" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177913</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R12-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R12-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23177914" alias="SHAH_H000019_T07_04_DLP01-A98179A-R03-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177914</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R03-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R03-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23177915" alias="SHAH_H000019_T07_04_DLP01-A98179A-R18-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177915</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R18-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R18-C13</LIBRARY_NAME>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23177916" alias="SHAH_H000019_T07_04_DLP01-A98179A-R14-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177916</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R14-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R14-C63</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177917</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177918</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177919</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177920</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177922" alias="SHAH_H000019_T07_04_DLP01-A98179A-R14-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177922</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R14-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R14-C15</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23177923" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177923</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R29-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R29-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177924</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R13-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R13-C15</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
  <EXPERIMENT accession="SRX23177925" alias="SHAH_H000019_T07_04_DLP01-A98179A-R09-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177925</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R09-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R09-C15</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177926</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177927</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177928</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177931" alias="SHAH_H000019_T07_04_DLP01-A98179A-R30-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177931</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R30-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177932</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177933</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177934</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177935</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177936</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177940" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177940</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177941</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177942</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177943</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177944</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177945</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177949" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177949</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23177950</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23177951</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23177952</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177953</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177954</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177961</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177967" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177967</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177968</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177969</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177970</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177971</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177972</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177976" alias="SHAH_H000019_T07_04_DLP01-A98179A-R04-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177976</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177977</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177978</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177979</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23177980</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177981</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23177985" alias="SHAH_H000019_T07_04_DLP01-A98179A-R14-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23177985</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23177986</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23177987</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177988</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23177989</PRIMARY_ID>
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      <PRIMARY_ID>SRX23177990</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23177994" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C26">
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177997</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23177998</PRIMARY_ID>
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      <PRIMARY_ID>SRX23177999</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23178003" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178003</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178004</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R18-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178005</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R28-C12</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178006</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R07-C12</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178007</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178008</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178012" alias="SHAH_H000019_T07_04_DLP01-A98179A-R15-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178012</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R15-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178013</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R06-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178014</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178015</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R19-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178016</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178017</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178021" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178021</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R29-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R29-C23</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23178022" alias="SHAH_H000019_T07_04_DLP01-A98179A-R13-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178022</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R13-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R13-C23</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178023</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R09-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R09-C23</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178024</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R05-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178025</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178026</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178027</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178030" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178030</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178031</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178032</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178033</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178034</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178039" alias="SHAH_H000019_T07_04_DLP01-A98179A-R05-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178039</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178040</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178041</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178042</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23178043</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178044</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178048" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178048</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178049</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178050</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178051</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178052</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178057" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C27">
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178059</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23178060</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178066" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178066</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178067</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178068</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178069</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23178070</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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  <EXPERIMENT accession="SRX23178075" alias="SHAH_H000019_T07_04_DLP01-A98179A-R09-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178075</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178076</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178077</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178078</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178079</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178084" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C16">
    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178086</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178087</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178088</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23178093" alias="SHAH_H000019_T07_04_DLP01-A98179A-R13-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178093</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178094</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178095</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178096</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23178097</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178098</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23178102" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178102</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23178103</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178104</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23178105</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178106</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178107</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23178111" alias="SHAH_H000019_T07_04_DLP01-A98179A-R07-C55">
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178112</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178113</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23178114</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178115</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178116</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23178120" alias="SHAH_H000019_T07_04_DLP01-A98179A-R30-C20">
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      <PRIMARY_ID>SRX23178120</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178121</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178122</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178123</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23178124</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23178138" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23178138</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178139</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23178140</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179117</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179118</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179119</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179132" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C35">
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179133</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179134</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179135</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179136</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179159" alias="SHAH_H000019_T07_04_DLP01-A98179A-R22-C41">
    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179161</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179162</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179163</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179177" alias="SHAH_H000019_T07_04_DLP01-A98179A-R03-C63">
    <IDENTIFIERS>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179178</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179179</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179180</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179181</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179195" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179195</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179196</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R19-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179197</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179198</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179199</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179200</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179204" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C65">
    <IDENTIFIERS>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179205</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179207</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179208</PRIMARY_ID>
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      <PRIMARY_ID>SRX23179209</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23179213" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179213</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179214</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179215</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179216</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179217</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179218</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179225</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179226</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23179231" alias="SHAH_H000019_T07_04_DLP01-A98179A-R13-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179231</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179232</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179233</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179234</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179235</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179236</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23179240" alias="SHAH_H000019_T07_04_DLP01-A98179A-R19-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179240</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179241</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179242</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179243</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179244</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179245</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23179249" alias="SHAH_H000019_T07_04_DLP01-A98179A-R26-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179249</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179250</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179251</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179252</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179253</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179267" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C67">
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179268</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179269</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179270</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179303" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C68">
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179304</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179305</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179306</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179307</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179308</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23179312" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179312</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179313</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R18-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179314</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179315</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R24-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179316</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179317</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179321" alias="SHAH_H000019_T07_04_DLP01-A98179A-R30-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179321</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179322</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179323</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179324</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179325</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179326</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179384" alias="SHAH_H000019_T07_04_DLP01-A98179A-R08-C11">
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      <PRIMARY_ID>SRX23179384</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179385</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179387</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179394</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179395</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23179396</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23179397</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23179402" alias="SHAH_H000019_T07_04_DLP01-A98179A-R30-C24">
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      <PRIMARY_ID>SRX23179402</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23179403</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23179404</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23180370</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23180395</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180396</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23180397</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180403" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180403</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180404</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180405</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23180406</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23180407</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180408</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23180412" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180412</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R06-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R06-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180413" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180413</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R16-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180414" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180414</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R20-C17</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180415" alias="SHAH_H000019_T07_04_DLP01-A98179A-R28-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180415</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R28-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R28-C17</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180416</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180417</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180418</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180419</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180420</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180421" alias="SHAH_H000019_T07_04_DLP01-A98179A-R15-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180421</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R15-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R15-C45</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180422" alias="SHAH_H000019_T07_04_DLP01-A98179A-R11-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180422</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R11-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23180423" alias="SHAH_H000019_T07_04_DLP01-A98179A-R30-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180423</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R30-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R30-C45</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180424</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R21-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180425</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180426</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180427</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180430" alias="SHAH_H000019_T07_04_DLP01-A98179A-R22-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180430</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180431</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180432</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180433</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180434</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23180451</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180466" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180466</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180467</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180468</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180469</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180470</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180471</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180475" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180475</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180476</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180477</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180478</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180479</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180484" alias="SHAH_H000019_T07_04_DLP01-A98179A-R07-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180484</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180485</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180486</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180487</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180488</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180493" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180493</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180494</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180495</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180496</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180497</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180498</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180511" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180511</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R21-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R21-C64</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180512" alias="SHAH_H000019_T07_04_DLP01-A98179A-R04-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R04-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R04-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180513" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180513</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R06-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R06-C64</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180514" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R20-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180515</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180516</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180517</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180518</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180519</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180520" alias="SHAH_H000019_T07_04_DLP01-A98179A-R23-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R23-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R23-C70</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180521" alias="SHAH_H000019_T07_04_DLP01-A98179A-R15-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180521</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R15-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R15-C70</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180522" alias="SHAH_H000019_T07_04_DLP01-A98179A-R11-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R11-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R11-C70</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180523" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180523</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R21-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180524</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180525</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180526</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180529" alias="SHAH_H000019_T07_04_DLP01-A98179A-R22-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180529</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R22-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180530</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180531</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180532</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180533</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180534</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180538" alias="SHAH_H000019_T07_04_DLP01-A98179A-R26-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180538</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180539</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180540</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180541</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180542</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180543</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180547</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180548</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180549</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180550</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180551</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180556</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180558</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180559</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180560</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180565" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180565</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180566</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R03-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180567</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180568</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180569</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180570</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180574" alias="SHAH_H000019_T07_04_DLP01-A98179A-R08-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180574</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180575</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180576</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180577</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23180578</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180579</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180583" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180583</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180584</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180585</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180586</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180587</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180588</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180592" alias="SHAH_H000019_T07_04_DLP01-A98179A-R13-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180592</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180593</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R09-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180594</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180595</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180596</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180597</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180601" alias="SHAH_H000019_T07_04_DLP01-A98179A-R03-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180601</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180602</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23180603</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23180604</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23180605</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23180606</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23180610" alias="SHAH_H000019_T07_04_DLP01-A98179A-R03-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180610</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R03-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180611</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R28-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180612</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180613</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180614</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180615</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180619" alias="SHAH_H000019_T07_04_DLP01-A98179A-R25-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180619</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R25-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R25-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180620" alias="SHAH_H000019_T07_04_DLP01-A98179A-R22-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180620</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R22-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R22-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180621" alias="SHAH_H000019_T07_04_DLP01-A98179A-R26-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180621</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R26-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R26-C33</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23180622" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180622</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R20-C33</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180623</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R18-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180624</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180625</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180626</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180627</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23180628" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180628</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180629</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R04-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180630</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180631</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180632</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23180633</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23180640</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181619</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181625" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181625</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R29-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181626</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181627</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181628</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181629</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181630</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181634" alias="SHAH_H000019_T07_04_DLP01-A98179A-R04-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181634</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R04-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181635</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181636</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181637</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181638</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181639</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181643" alias="SHAH_H000019_T07_04_DLP01-A98179A-R28-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181643</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181644</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181645</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181646</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181647</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181648</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181652" alias="SHAH_H000019_T07_04_DLP01-A98179A-R15-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181652</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181653</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181654</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181655</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181661" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181661</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181662</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181663</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181664</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181665</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181666</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181670</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23181671</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23181672</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181673</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181679</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181680</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181681</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181682</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181688" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181688</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181689</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181690</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181691</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181692</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181693</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181697" alias="SHAH_H000019_T07_04_DLP01-A98179A-R27-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181697</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181698</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181699</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181700</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181701</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181702</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181706" alias="SHAH_H000019_T07_04_DLP01-A98179A-R10-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181706</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R10-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R10-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181707" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181707</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R17-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R17-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181708" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R06-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R06-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181709" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181709</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R16-C49</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181710</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181711</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181712</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181713</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181714</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23181715" alias="SHAH_H000019_T07_04_DLP01-A98179A-R17-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181715</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R17-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R17-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181716" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R06-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R06-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181717" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181717</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R12-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R12-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181718" alias="SHAH_H000019_T07_04_DLP01-A98179A-R20-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R20-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R20-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181719</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R28-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181720</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181721</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181722</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181723</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181724" alias="SHAH_H000019_T07_04_DLP01-A98179A-R08-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181724</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R08-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R15-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R11-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R21-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181728</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181729</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181733" alias="SHAH_H000019_T07_04_DLP01-A98179A-R29-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181733</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R13-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R09-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181736</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181737</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181738</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181742" alias="SHAH_H000019_T07_04_DLP01-A98179A-R04-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181742</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181743</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181744</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181745</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23181746</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181751" alias="SHAH_H000019_T07_04_DLP01-A98179A-R26-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181751</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R18-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181753</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181754</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181755</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181756</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181760" alias="SHAH_H000019_T07_04_DLP01-A98179A-R23-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181760</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181761</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181762</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181763</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181764</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181765</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181769" alias="SHAH_H000019_T07_04_DLP01-A98179A-R09-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181769</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181770</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181771</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181772</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23181773</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181778</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181779</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23181780</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23181781</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181787" alias="SHAH_H000019_T07_04_DLP01-A98179A-R07-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181787</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181788</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181789</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181790</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181791</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181792</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181796" alias="SHAH_H000019_T07_04_DLP01-A98179A-R27-C03">
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      <PRIMARY_ID>SRX23181796</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181797</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181798</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181799</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23181800</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181805" alias="SHAH_H000019_T07_04_DLP01-A98179A-R06-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R06-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181806" alias="SHAH_H000019_T07_04_DLP01-A98179A-R16-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R16-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R16-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23181807" alias="SHAH_H000019_T07_04_DLP01-A98179A-R25-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R25-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R25-C03</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181808</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R19-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181809</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181810</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181814" alias="SHAH_H000019_T07_04_DLP01-A98179A-R19-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181814</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R19-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R19-C66</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181815" alias="SHAH_H000019_T07_04_DLP01-A98179A-R22-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R22-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R22-C66</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181816</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R12-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R12-C66</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
  <EXPERIMENT accession="SRX23181817" alias="SHAH_H000019_T07_04_DLP01-A98179A-R03-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R03-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126458</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R03-C66</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181818</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181819</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181820</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181823" alias="SHAH_H000019_T07_04_DLP01-A98179A-R14-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R14-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181824</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R09-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T07_04_DLP01-A98179A-R09-C44</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181825</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181826</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R05-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181827</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181828</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181832" alias="SHAH_H000019_T07_04_DLP01-A98179A-R21-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181832</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181833</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181834</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181835</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181836</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181837</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181841" alias="SHAH_H000019_T07_04_DLP01-A98179A-R18-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181841</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181842</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181843</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181844</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23181845</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181850" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181850</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181851</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181852</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181853</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181854</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181855</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181859</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23181860</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181861</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181862</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181863</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181868</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181869</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23181870</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181871</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23181872</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181877" alias="SHAH_H000019_T07_04_DLP01-A98179A-R12-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181877</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181878</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181879</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23181880</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23181881</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23181886" alias="SHAH_H000019_T07_04_DLP01-A98179A-R11-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181886</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T07_04_DLP01-A98179A-R11-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181887</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181888</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23181889</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T07_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193528</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193529</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193530</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23193533" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193533</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C35</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193534" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193534</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193535" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193535</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193537</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193539</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193540</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23193542" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C62</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193543</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C39</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193545" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193545</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C39</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193547</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193548</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193549</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193550</PRIMARY_ID>
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    </IDENTIFIERS>
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  <EXPERIMENT accession="SRX23193551" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193551</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C39</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193552</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193553</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R21-C39</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193554</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C39</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193555</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193556</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193557</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193558</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193559</PRIMARY_ID>
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    </IDENTIFIERS>
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  <EXPERIMENT accession="SRX23193560" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193560</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193561</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193562</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C41</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193563</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C41</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193565</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193566</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23193567</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23193569" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C41">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193569</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193570</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193571</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193572</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193573</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193574</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193578</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193579</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23193580</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23193581</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23193582</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193583</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193584</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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  <EXPERIMENT accession="SRX23193587" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193587</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193588</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193589</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193590</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193591</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193592</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193593</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193594</PRIMARY_ID>
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  <EXPERIMENT accession="SRX23193596" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193596</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193597</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193598</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C59</LIBRARY_NAME>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193599</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193600</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193601</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193602</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193605" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193605</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193606</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193607</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C59</LIBRARY_NAME>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193608</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193609</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193610</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193611</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193612</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193614" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193614</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193615" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193615</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193616" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193616</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193617" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193617</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193618" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193618</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193619" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193619</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193620</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193621</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193622</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193623" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193623</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193624" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193624</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193625" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193625</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193626" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193626</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193627" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193627</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193628" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193628</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193629</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193630</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193631</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193632" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193632</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193633</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193634</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193635" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193635</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193636</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193637</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193638</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193639</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193640</PRIMARY_ID>
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    </IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193650" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193650</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193651</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193652</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193653" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193653</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193654</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193655</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193656</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193657</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193658</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193659" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193659</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193660</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193661</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C25</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193662</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193663</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193664</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193665</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193666</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193668</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193669</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193670</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193671</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193672</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193673</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23193674</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193677" alias="SHAH_H000019_T05_04_DLP01-A108851A-R19-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193677</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R19-C30</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193678</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C30</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193679</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C30</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  <EXPERIMENT accession="SRX23193680" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193680</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193681</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193682</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193683</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23193686" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193686</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C64</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193687</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193688</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C67</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193689</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193690</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193691</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193692</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193693</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23193695</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194673</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194674</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194676</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194680</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23194681</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194682</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23194683</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23194684</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194685</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194689</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194690</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194691</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194692</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194693</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194694</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194695</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194698</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194699</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194700</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194701</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194702</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194703</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194704</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194707" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C41">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194707</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C41</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194708" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194709" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194709</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C17</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194710" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C17</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194711</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194712" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194713</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194714</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194715</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194716" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194717" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194717</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194718" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C17</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194719" alias="SHAH_H000019_T05_04_DLP01-A108851A-R21-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194719</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R21-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194720" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194721" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194721</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194723</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194724</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194725" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194726" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194727" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194728" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194728</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194729</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194730</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194731</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194732</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194733</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194734" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C13</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C18</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C18</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194738</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194740</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194741</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194743" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194743</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194746</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194747</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194748</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194749</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194752</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194754</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194755</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194756</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194757</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194758</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194759</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194761" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194761</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194763</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C19</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194765</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194766</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194767</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194768</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194769</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194770" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194770</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194771</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194772</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194773</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194774</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194775</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194776</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194779" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194780</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C22</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194781</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C22</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194782</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194783</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194784</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194785</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194786</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194787</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194788" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194788</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C40</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194791</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194792</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194793</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194794</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194795</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194797" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194799</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194800</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194801</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194802</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23194803</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23194806" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194808</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194810</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194811</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23194812</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23194813</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195940" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195940</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195941" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195941</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195942" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195942</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195943" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195943</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195944</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195945</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195946</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195947</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195948</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195949" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195949</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C42</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195950</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195951</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C61</LIBRARY_NAME>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195952</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195953</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195954</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195955</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23195956</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23195957</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195958" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195958</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C61</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195959</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195960</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C61</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195961</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195962</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195963</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195964</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195965</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23195966</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195967" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195967</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C53</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195968</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195969</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195970</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195971</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195972</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195973</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23195974</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195976" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195976</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C53</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195977</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C53</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195978</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C53</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195979</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C53</LIBRARY_NAME>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195980</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195981</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195982</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23195983</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195985" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195985</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C17</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195986" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195986</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195987" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195987</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C17</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195988" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195988</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195989</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195990</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195991</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195992</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195993</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23195994" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195994</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195995</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195996</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195997</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195998</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23195999</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196000</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196001</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23196002</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196003" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196003</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196004" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196004</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196005" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196005</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196006</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196007</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196008</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196009</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196010</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23196011</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196012" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196012</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196013</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196014" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196014</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196015" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196015</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196016</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196017</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196018</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196019</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23196020</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196021" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196021</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196022" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196022</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196023" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196023</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196024" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196024</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196025" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196025</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196026" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196026</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196027" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196027</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196028" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196028</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196029</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196030" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196030</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196031" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196031</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196032" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196032</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196033" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196033</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196034</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196035</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196036</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196037</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196038</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196039" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196039</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196040" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196040</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196041" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196041</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196042" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196042</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196043" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196043</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196044" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196044</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196045</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196046</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196047</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196048" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196048</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196049" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196049</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196050" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196050</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C65</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196051" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196051</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196052</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C65</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196053" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196053</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196054</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196055</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196056</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196057" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196057</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C38</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196058</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196059</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C38</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196060" alias="SHAH_H000019_T05_04_DLP01-A108851A-R21-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196060</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R21-C38</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196061</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196062</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196063</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196064</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23196065</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196066" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196066</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196067" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196067</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196068" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196068</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196069" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196069</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196070</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196071</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196072</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196073</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196074</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196075" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196075</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196076</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196077" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196077</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196078" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196078</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196079</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C22</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196080" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196080</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196081</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196082</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196083</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196084" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196084</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196085" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196085</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196086" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196086</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196087" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196087</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196088</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196089</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196090</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196091</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196092</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196093" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196093</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196094" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196094</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196095" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196095</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C40</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196096" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196096</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C40</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196097</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196098</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196099</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196100</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196101</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196102" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196102</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C26</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196103</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C26</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196104</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196105</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196106</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196107</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196108</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23196109</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196111" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196111</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196112" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196112</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196113</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R19-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196114</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196115</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196116</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196117</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196118</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196119</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23196120" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196120</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196121</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196122</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C67</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196123</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C67</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196124</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23196125</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197214</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197215</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197216</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197217" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197217</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197218" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197219" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197219</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197220" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197221" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197221</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197222" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197223</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197224" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197225</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      <ILLUMINA>
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      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197226" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197226</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C35</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197227</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197228</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C35</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197229</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197230</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197231</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197232</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23197233</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197234</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197235" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197235</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C56</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197236</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197237</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R21-C56</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197239</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197241</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197242</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197244" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197244</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197245" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197245</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197246" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197246</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197247</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197249</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197250</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197251</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197252</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197253" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197253</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197254</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197255</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197257</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197258</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197259</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197260</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197262" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197262</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C15</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197263</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197264" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197264</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197265</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197266</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197267</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197268</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197269</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197280</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197281</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197282</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197283</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23197284</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197285</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197298" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197298</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C38</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197299</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197300</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C38</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197301</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197302</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197303</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197304</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197305</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197306</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197307" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197307</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197308</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197309</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197310" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197310</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197311</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197312</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197313</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197314</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197315</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197316" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197316</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197317" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197317</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197318" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197318</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197319" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197319</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197320" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197320</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197321" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197321</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197322" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197322</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197323" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197323</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197324</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197325" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197325</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197326" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197326</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197327" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197327</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197328" alias="SHAH_H000019_T05_04_DLP01-A108851A-R19-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197328</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R19-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197329" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197329</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197330" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197330</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C26</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197331</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197332</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197333</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197334" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197334</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197335</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197336</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197337</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197338</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197339</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197340</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197490" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197490</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197491</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197492</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197493</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197494</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197495</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197496</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197499" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197499</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197500" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197500</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197501" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197501</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C36</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197502</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C36</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197503</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C36</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197504</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197505</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197506</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197507</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197508" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197508</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197509" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197509</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197510" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197510</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197511" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197511</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197512" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197513" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197513</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197514" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C68</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197515" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197515</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197516</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197517" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197517</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197518" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197518</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197519" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197519</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197520" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197521" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197521</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197522" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197523" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197523</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197524" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197524</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C09</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197525" alias="SHAH_H000019_T05_04_DLP01-A108851A-R21-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197525</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R21-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197526" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197526</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197527" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197527</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197528" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197528</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197529" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197529</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197530" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197530</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197531" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197531</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197532</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197533</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197534</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197535" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197535</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197536" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197537" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197537</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197538" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197539" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197539</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197540" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197540</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197541</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197543</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197544" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197545" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197545</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197546" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C37</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197547" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197547</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197548" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197548</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197549" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197549</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C37</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197550</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197551</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197552</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197553" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197553</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197554</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197555" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197555</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197556" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197556</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197557</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197558</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197559</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197560</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197561</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197562" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197562</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197563" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197563</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197564" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197565" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197565</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197566" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197566</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197567" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197567</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197568</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197569</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197570</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197571" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197571</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197572</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197573</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C33</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197574" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197574</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197575</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197576</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197577</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197578</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23197579</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197580" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197580</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197581</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197582" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197582</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197583" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197583</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197584</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197585</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197586</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197587</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197588</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197589" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197589</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197590" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197590</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197591" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197591</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197592" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197592</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197593</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197594</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197595</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197596</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197597</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197598" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197598</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197599" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197599</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197600" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197600</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C07</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197601" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197601</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C07</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197602</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C07</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197603</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C42</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197604</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197605</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197606</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197607" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197607</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197608" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197608</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197609" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197609</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197610" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197610</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197611" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197611</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197612" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197612</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197613" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197613</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197614" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197614</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197615</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C42</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197616" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197616</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197617" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197617</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197618" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197618</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197619" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197619</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197620" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197620</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197621" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197621</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197622" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197622</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197623" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197623</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197624" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197624</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197625" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197625</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197626" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197626</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197627" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197627</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197628" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197628</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197629" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197629</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197630" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197630</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197631" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197631</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C39</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197632" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197632</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197633" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197633</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C39</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197634" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197634</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197635" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197635</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197636" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197636</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197637" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197637</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197638" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197638</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197639" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197639</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197640</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197641</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197642</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197643</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23197644</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197645</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197646</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197648</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197652</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23197653</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23197654</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23197655</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197661</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197662</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197663</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197664</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197665</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197666</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197667</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197670" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197670</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197671</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C48</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197673</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197674</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197675</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197676</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197677</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197678</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197679" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197679</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C48</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197680</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197681</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C48</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197682</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197683</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197684</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197685</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23197686</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197688" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197688</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197689</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197690</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197691</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197692</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197693</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197694</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23197695</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197697" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197697</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197698" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197698</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197699" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197699</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197700" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197700</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197701" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197701</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197702" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197702</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197703</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197704</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197705</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197706" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197706</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197707" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197707</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197708" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197709" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197709</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197710" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197711" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197711</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C19</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197713</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197714</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197715" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197715</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197716" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197717" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197717</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197718" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197719" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197719</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197720" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197721" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197721</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197722" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197723" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197723</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197724" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197724</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197725" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197726" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197727" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197728" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197728</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197729" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197729</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197730" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197730</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197731" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197731</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197732" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197732</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197733" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197733</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197734" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197735" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197736" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197737" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197738" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197738</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197739" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197740" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197740</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197741</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197742" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197742</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197743" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197743</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197744" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197745" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197746" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197746</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197747" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197747</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197748</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197749" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197749</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197750</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197751" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197751</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197754</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197755</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197756</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197757</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197758</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197759</PRIMARY_ID>
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    </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197760" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197760</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197761" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197761</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197762" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197763" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197763</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197764" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197765" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197765</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197766</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C68</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197767</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197768</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C68</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197769" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197769</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197770" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197770</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197771" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197771</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197772" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197772</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197773" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197773</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C68</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197774" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197774</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197775</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197776</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197777</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197778" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197778</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197779" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197780" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197780</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197781" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197781</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197782" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197782</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197783" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197783</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197784</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197785</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197786</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197787" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197787</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197788" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197788</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197789" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197790" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197791" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197791</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197792" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197792</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197793</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197794</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C09</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197795</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197796" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197796</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197797" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197798" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197799" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197799</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197800" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197800</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197801" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197801</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C44</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197802</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197803</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197804</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197805" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197806" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197807" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197808" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197808</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197809" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197810" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197810</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197811</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197812" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197812</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197813</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197814" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197814</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197815" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197816" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197816</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197817" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197818" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197818</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197819" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197820" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197820</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197821" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197822" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197822</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197823" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197824" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197824</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197825" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197826" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197826</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197827" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197828" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197828</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197829" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197830" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197830</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197831" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197832" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197832</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197833" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197834" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197834</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197835" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197836" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197836</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197837" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197838" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197838</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197839" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197840" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197840</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197841" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197842" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197842</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197843" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197844" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197844</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197845" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197845</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197846" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197846</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197847</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197848" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197848</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197849</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197850" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197850</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197851" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197851</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197852" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197852</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197853" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197854" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197854</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23197855" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197856</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197857</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23197858</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198467</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198468</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198469</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198470</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198471</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198472</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23198473</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198476</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198477</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198478</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23198479</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198481</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198485" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198485</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C29</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198486</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198487</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198488</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198489</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198490</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198491</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23198492</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23198493</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198494" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198494</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C70</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198495</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C70</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198496</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198497</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198498</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198499</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23198500</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198503" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198503</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198504</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198505</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198506" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198506</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198507</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198508</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198509</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198510</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198511</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198512" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198513" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198513</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198514" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198515" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198515</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198516" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198516</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198517" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198517</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198518" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198518</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198519" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198519</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198520" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198521" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198521</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198522" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198523" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198523</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198524" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198524</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198525" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198525</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198526" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198526</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198527" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198527</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198528" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198528</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198529" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198529</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198530" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198530</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198531" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198531</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198532" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198532</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198533" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198533</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198534" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198534</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198535" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198535</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198536" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198537" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198537</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198539" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198539</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198540" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198540</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198541" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198541</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198542" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198543" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198543</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198544" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198545</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198547</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198548" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198548</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198549" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198549</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198550" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198550</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198551" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198551</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198552" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198552</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198553" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198553</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198554</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198555</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198556</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198557" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198557</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198558" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198558</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198559" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198559</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198560" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198560</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198561</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198562</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198563</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198565</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198566" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198566</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198567" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198567</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198568" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198568</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198569" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198569</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198570</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198571" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198571</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C21</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198572</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198573</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198574</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198575" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198575</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198576" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198576</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198577" alias="SHAH_H000019_T05_04_DLP01-A108851A-R19-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198577</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R19-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198578" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198578</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198579</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R21-C11</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198580" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198580</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198581</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198582</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198583</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198584" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198584</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198585" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198585</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198586" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198586</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198587" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198587</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198588" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198588</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198589" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198589</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C11</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198590</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198591</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198592</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198593" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198593</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198594" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198594</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198595" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198595</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198596" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198596</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198597" alias="SHAH_H000019_T05_04_DLP01-A108851A-R04-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198597</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198598" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198598</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C07</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198599</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198600</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198601</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198602" alias="SHAH_H000019_T05_04_DLP01-A108851A-R24-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198602</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198603" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198603</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198604" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198604</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C24</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198605" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198605</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198606</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198607</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198608</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198609</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198610</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198611" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198611</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198612" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198612</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198613" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198613</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198614" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198614</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198615" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198615</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198616" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198616</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198617" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198617</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198618" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198618</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198619" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198619</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198620" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198620</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198621" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198621</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198622" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198622</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198623" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198623</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198624" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198624</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198625" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198625</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198626" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198626</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C35</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198627" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C41">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198627</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C41</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198628" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C41">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198628</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C41</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198629" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198629</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198630" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198630</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198631" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198631</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198632" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198632</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198633" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198633</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198634" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198634</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198635" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198635</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198636" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198636</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198637" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198637</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198638" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198638</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198639" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198639</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198640" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198640</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198641" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198641</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198642</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198643" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198643</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198644</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198645</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198646</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198647" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198647</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C13</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198648</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198649</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C13</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198650</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198651</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198652</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198653</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23198654</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198656</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198657</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198658</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198659</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198660</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198661</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23198662</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198665" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198665</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198666" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198666</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198667" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198667</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198668" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198668</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198669</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198670</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C59</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198671</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198673</PRIMARY_ID>
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    </IDENTIFIERS>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198674" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198674</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198675" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198675</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198676" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198676</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198677" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198677</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198678</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198679</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198680</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198681</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198682</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198683" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198683</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C69</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198684</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198685</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198686" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198686</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198687</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198688</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198689</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198690</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198691</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198692</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198693</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198694</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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      <PRIMARY_ID>SRX23198695</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198697</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23198698</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198701" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198701</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198702" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198702</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198703" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198703</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198704" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198704</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198705" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198705</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198706" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198706</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198707</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C65</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198708" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C65</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198709</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198710" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198711" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198711</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198712" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198713" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198713</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198714" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198714</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198715" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198715</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198716" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198717" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198717</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198718" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198719" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198719</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198720" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198721" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198721</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198722" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198723" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198723</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198724" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198724</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198725" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198726" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198727" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198728" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198728</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198729" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198729</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198730" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198730</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198731" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198731</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198732" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198732</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198733" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198733</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198734" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198735" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198736" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198737" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198738" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198738</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198739" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198740" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198740</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198741" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198741</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198742" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198742</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198743" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198743</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198744" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198745" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198746" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198746</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198747" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198747</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198748" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198748</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198749" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198749</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198750" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198750</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C40</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198751" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C40">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198751</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C40</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C40</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C40</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198754</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C40</LIBRARY_NAME>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198755" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198755</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198756" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198756</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198757" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198757</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198758" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198758</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198759" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198759</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198760" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198760</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198761</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C30</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198763</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198764" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198765" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198765</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198766" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198766</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198767" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198767</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198768" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198768</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198769" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198769</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C64</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198770</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C64</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198771</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198772</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198773" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198773</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198774" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198774</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198775" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198775</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198776" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198776</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198777</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198778</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198780</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198781</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198782" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198782</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198783" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198783</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198784" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198784</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198785" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198785</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198786" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198786</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198787" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198787</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198788</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198791" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198791</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198792" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198792</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198793" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198793</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198794" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198794</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198795" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198795</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198796" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198796</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C70</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C70</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198799</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198800" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198800</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198801" alias="SHAH_H000019_T05_05_DLP01-A108833A-R06-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198801</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198802" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198802</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198803" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198803</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198804" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198804</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198805" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198808</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198809" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198810" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198810</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C68</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198811" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198811</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198812" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198812</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198813" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198813</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198814" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198814</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198815" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198816" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198816</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198817" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198818" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198818</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198819" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198820" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198820</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198821" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198822" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198822</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198823" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198824" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198824</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198825" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198826" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198826</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198827" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198828" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198828</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198829" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198830" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198830</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198831" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198832" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C09">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198832</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C09</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198833" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198834" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198834</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198835" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198836" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198836</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198837" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198838" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198838</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198839" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198840" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198840</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198841" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198842" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198842</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198843" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198844" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198844</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198845" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198845</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198846" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198846</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198847" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198847</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198848" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198848</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198849" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198849</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198850" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198850</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198851" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198851</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198852" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198852</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198853" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198854" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198854</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198855" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198856" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198856</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198857" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198857</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198858" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198858</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198859" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198859</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198860" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198860</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198861" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198861</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198862</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198863" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198863</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198864" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198864</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198865" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198865</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198866" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198866</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198867" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198867</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198868" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198868</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198869" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198869</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198870</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198871</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198872" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198872</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198873" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198873</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198874" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198874</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198875" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198875</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198876" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198876</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198877" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198877</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198878" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198878</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198879" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198879</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198880" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198880</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198881" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198881</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198882" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198882</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198883" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198883</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198884" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198884</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198885" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198885</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198886" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198886</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198887" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198887</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198888" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198888</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198889</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198890" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198890</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198891" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198891</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198892" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198892</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198893" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198893</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198894" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198894</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198895" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198895</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198896" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198896</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198897" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198897</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C20</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198898" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198898</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198899" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198899</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198900" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198900</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198901" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198901</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198902" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198902</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198903" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198903</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198904" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198904</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198905</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198906</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198907</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198908" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198908</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198909" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198909</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198910" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198910</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198911" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198911</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198912" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198912</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198913" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198913</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23198914" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23198914</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199731" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199731</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199732</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199733" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199733</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199734" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199735" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199736" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199737" alias="SHAH_H000019_T05_04_DLP01-A108851A-R12-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R12-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199738" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199738</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C70</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199740</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199741</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199742" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199742</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199743" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199743</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199744" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199745" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199746" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199746</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R15-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199747</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199748</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199749</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199750</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C23</LIBRARY_NAME>
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          <PAIRED/>
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      <ILLUMINA>
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    </PLATFORM>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199751" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199751</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199754</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199755</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199756</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199757</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199758</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199759</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199760" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199760</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C23</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199761</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C36</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199763</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C46</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199765</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199766</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199767</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199768</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199769" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199769</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199770</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199771</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199772</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199773</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199774</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199775</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199778</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199780</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199781</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199782</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199783</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199784</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199787" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199787</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C03</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199788</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R04-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199789" alias="SHAH_H000019_T05_04_DLP01-A108851A-R06-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C03</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C03</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199791</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199792</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199793</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199794</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199796" alias="SHAH_H000019_T05_04_DLP01-A108851A-R17-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199796</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R17-C27</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R04-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C27</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199799</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199800</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199801</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199802</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199803</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199804</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199805" alias="SHAH_H000019_T05_04_DLP01-A108851A-R20-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C27</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199808</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C09</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199810</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199811</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199812</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199813</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199814" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199814</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C32</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199815" alias="SHAH_H000019_T05_04_DLP01-A108851A-R07-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R07-C32</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199816" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199816</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199817" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199818" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199818</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199819" alias="SHAH_H000019_T05_04_DLP01-A108851A-R11-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R11-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199820" alias="SHAH_H000019_T05_04_DLP01-A108851A-R16-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199820</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199821" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R25-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199822" alias="SHAH_H000019_T05_04_DLP01-A108851A-R19-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199822</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R19-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199823" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199824" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199824</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199825" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199826" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199826</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C10</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199827" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199828" alias="SHAH_H000019_T05_04_DLP01-A108851A-R18-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199828</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R18-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R18-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199829" alias="SHAH_H000019_T05_04_DLP01-A108851A-R28-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R28-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199830" alias="SHAH_H000019_T05_04_DLP01-A108851A-R14-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199830</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199831" alias="SHAH_H000019_T05_04_DLP01-A108851A-R29-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R29-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R29-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199832" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199832</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R13-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199833" alias="SHAH_H000019_T05_04_DLP01-A108851A-R09-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R09-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R09-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199834" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199834</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199835" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126675" refname="SHAH_H000019_T05_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199836" alias="SHAH_H000019_T05_04_DLP01-A108851A-R27-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199836</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199837" alias="SHAH_H000019_T05_04_DLP01-A108851A-R23-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199838</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199840</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199841" alias="SHAH_H000019_T05_04_DLP01-A108851A-R21-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R21-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199842</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R10-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R23-C31</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199844</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199845</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199846</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199847</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199848</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199850" alias="SHAH_H000019_T05_04_DLP01-A108851A-R26-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199850</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C31</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199851</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R24-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199852</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R14-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R14-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199853" alias="SHAH_H000019_T05_04_DLP01-A108851A-R13-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R13-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199854</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R11-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199857</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199858</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199859</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199860" alias="SHAH_H000019_T05_04_DLP01-A108851A-R10-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199860</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R10-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199861</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R06-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R06-C24</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199862</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R16-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R16-C24</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199863</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199864</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199865</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199866</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199867</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199869" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199869</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C42</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199870</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199871</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C42</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199872</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199873</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199874</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199875</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199876</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199877</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199878" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199878</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C35</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199879</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199880" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C35">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199880</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C35</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199881</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C35</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C35</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199882</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199883</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199884</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199885</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199886</PRIMARY_ID>
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    </IDENTIFIERS>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199887" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199887</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C62</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199888</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C62</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199889</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C62</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199890</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199891</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199892</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199893</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199894</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23199895</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199896" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199896</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C61</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199897</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199898</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199899</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C61</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199900</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199901</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199902</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199903</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199904</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199905" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199905</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199906" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C39">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199906</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C39</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C39</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199907" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199907</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199908" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199908</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199909" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199909</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199910" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199910</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199911" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199911</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199912" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199912</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199913" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199913</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199914" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199914</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199915" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199915</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199916" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199916</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199917" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199917</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199918" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199918</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199919" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199919</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199920</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C53</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199921</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199922</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199923" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199923</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199924" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199924</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199925" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199925</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199926" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199926</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199927" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199927</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199928" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199928</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199929</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199930</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199931</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199932" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199932</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199933" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199933</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199934" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199934</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199935" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199935</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199936</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199937</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C41</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199938</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C41</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199939</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199940</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199941" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199941</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199942" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199942</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199943" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199943</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C17</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199944" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199944</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199945</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199946</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199947</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199948</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199949</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199950" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199950</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199951</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199952</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199953</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199954</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199955</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199956</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199957</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199958</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199959" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199959</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C63</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199960</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C63</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199961</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199962</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199963</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C63</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199964</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199965</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199966</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199967</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199968" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C63">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199968</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C63</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199969</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C63</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199970</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199971</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199972</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199973</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199974</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199977" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199977</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C59</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199978</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199979</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C59</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199980" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199980</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C59</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199981</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199982</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199983</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199984</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23199985</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199986" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199986</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199987" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199987</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199988" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199988</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199989</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C69</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199990</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C69</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199991</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199992</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199993</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199994</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23199995" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C69">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199995</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199996</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C69</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199997</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199998</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23199999</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200000</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200004" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200004</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200005" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200005</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200006" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200006</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200007" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C38">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200007</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C38</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C38</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200008" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200008</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200009" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200009</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200010</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200011</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200012</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200013" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200013</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200014" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200014</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200015" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200015</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200016" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200016</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200017" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200017</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200018" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200018</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200019</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200020</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200021</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200022" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200022</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200023" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200023</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200024" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200024</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200025" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200025</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200026" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200026</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200027" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200027</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200028</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200029</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200030</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200031" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200031</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200032" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200032</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200033" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200033</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200034" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200034</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200035</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200036</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C50</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200037</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200038</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200039</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200040" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200040</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C52</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200041</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200042</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C52</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200043</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200044</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200045</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200046</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200047</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200048</PRIMARY_ID>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200049" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200049</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200050</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C52</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200051</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200052</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200053</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200054</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200055</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200056</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200057</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200058" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200058</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C54</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200059</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200060</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200061</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200062</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200063</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200064</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200065</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200066</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200067" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200067</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C26</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200068</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C26</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200069</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C26</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200070</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200071</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200072</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200073</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200074</PRIMARY_ID>
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      <PRIMARY_ID>SRX23200075</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200076" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200076</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C26</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200077</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C26</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200078</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C26</LIBRARY_NAME>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200079</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200080</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200081</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200082</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200083</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200084</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200085</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200086</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C64</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200087</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C64</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200088</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200089</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200090</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200091</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200094" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C64">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200094</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C64</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200095</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C64</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200096</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C64</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200097</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C64</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200098</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200099</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200100</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200101</PRIMARY_ID>
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      <PRIMARY_ID>SRX23200102</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200103" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200103</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C67</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200104</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200105</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C67</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200106</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200107</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200108</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200109</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200110</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200111</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200112" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200112</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200113" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200113</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200114" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C67">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200114</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C67</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C67</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200115" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200115</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200116</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C70</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200117</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200118</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200119</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200120</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200121" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200121</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C70</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200122</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C70</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200123" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C70">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200123</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C70</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200124</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C70</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C70</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200125</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200126</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200127</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200128</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200130" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200130</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200131</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200132</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200133</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200134</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200135</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200136</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200139" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200139</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C23</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200140</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200141</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C23</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200142</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200143</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200144</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200145</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200148" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200148</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200149</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200150</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C51</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200151</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200152</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200153</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200154</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
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      <PRIMARY_ID>SRX23200155</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200157" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200157</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200158</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200159</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200160</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200161</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200162</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200163</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200164</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200165</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200166</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23200167</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200168</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200169</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200170</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200171</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200175" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200175</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200176</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200177" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200177</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200178</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200179</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200180</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200181</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200182</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200183</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200184" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200184</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200185</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C27</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200186</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C27</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200187</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200188</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200189</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200190</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23200191</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200192</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200193" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200193</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C27</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200194</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C27</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200195</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C66</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200196</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200197</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200198</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200199</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200200</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200201</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200202" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200202</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200203</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C66</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200204" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200204</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C66</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200205</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200206</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200207</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200208</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200209</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200210</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200211" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200211</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200212" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200212</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200213" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200213</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200214" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200214</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200215" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200215</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200216" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200216</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C37</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200217</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C32</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200218" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C32</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200219" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200219</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C32</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200220" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C32</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200221" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200221</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C32</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C32</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200223</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C32</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200225</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200226</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200227</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200228</PRIMARY_ID>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200229" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200229</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200230" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200230</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200231" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200231</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200232" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200232</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200233</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200234</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200235</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200236</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200237</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200238" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200239" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200239</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200240" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200241" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200241</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200242</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200243</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200244</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200245</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200246</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200247" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C34">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200247</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C34</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C34</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200249</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C34</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200250</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C34</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C34</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200251</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200252</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200253</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200254</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200255</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200256" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200257" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200257</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200258" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200258</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200259" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200259</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C33</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200260</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C33</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200261</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C33</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200262</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200263</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200264</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200265" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C33">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200265</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200266</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C33</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200267</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200268</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200269</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200270</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200271</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200272</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200274" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200274</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200275</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200276</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200277</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200278</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200279</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23200280</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200283" alias="SHAH_H000019_T05_05_DLP01-A108833A-R24-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200283</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200284" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200284</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200285" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200285</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200286" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200286</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200287" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200287</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200288" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200288</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200289</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200290</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200291</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200292" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200292</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C47</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200293</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200294" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200294</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C47</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23200295" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200295</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200296</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200297</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200298</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23200299</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23200301" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C07">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200301</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C07</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200302</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C07</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200303</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C07</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200304</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C07</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C07</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200305</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23200306</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201043</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201044</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201045</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201046</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201047</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201048</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R23-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201049</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201050</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201051</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201052</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201055</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201056</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201057</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201058</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201059</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201060</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201064" alias="SHAH_H000019_T05_04_DLP01-A108851A-R03-C68">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201064</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R03-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R03-C68</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201065</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R26-C68</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201066</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R20-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R20-C68</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201067</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R28-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201068</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201069</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R07-C68</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201070</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201073</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201074</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201075</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201076</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201077</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201078</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201082" alias="SHAH_H000019_T05_04_DLP01-A108851A-R08-C66">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201082</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201083</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C66</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201084</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201085</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201086</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201087</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201088</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201091" alias="SHAH_H000019_T05_04_DLP01-A108851A-R22-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201091</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201092</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201093</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R26-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201094</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R24-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201095</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201096</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201097</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201098</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23201100" alias="SHAH_H000019_T05_04_DLP01-A108851A-R15-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201100</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201101</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201102</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201103</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201104</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201105</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201106</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201109</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201110</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201111</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201112</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201114</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201118" alias="SHAH_H000019_T05_04_DLP01-A108851A-R25-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201118</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201119</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R19-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R19-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201120</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R22-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R22-C16</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201121</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R12-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201122</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201123</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201124</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201136</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201137</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201138</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201139</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201140</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201141</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201142</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201145</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201146</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R15-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201147</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23201148</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201149</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201150</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201154</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201155</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201156</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23201157</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201159</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201163</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201164</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201165</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201166</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201172</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201173</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R17-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201174</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201175</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201176</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201177</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201178</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201181</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201182</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23201183</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201184</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201190</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201191</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R25-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201192</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201193</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201194</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201195</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    <DESIGN>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201199" alias="SHAH_H000019_T05_04_DLP01-A108851A-R05-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201199</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R05-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126675</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R05-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201200</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R08-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R08-C11</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201201</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R27-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R27-C11</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201202" alias="SHAH_H000019_T05_04_DLP01-A108851A-R30-C11">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201202</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_04_DLP01-A108851A-R30-C11</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_04_DLP01-A108851A-R30-C11</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201203</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C62</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201204</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201205</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201206</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201207</PRIMARY_ID>
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    </IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201208" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201208</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201209" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201209</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201210" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201210</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C62</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201211" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201211</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201212" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201212</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201213" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201213</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201214</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201215</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201216</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201217" alias="SHAH_H000019_T05_05_DLP01-A108833A-R15-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201217</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201218" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201219" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201219</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201220" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201221" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201221</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201222" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201223</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201225</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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      <ILLUMINA>
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      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201226" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201226</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C57</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201227</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201228" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201228</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201229</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201230</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201231</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201232</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201233</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201234</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201235" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201235</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201236" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201236</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C53</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201237" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201237</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C53</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201238" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C53">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C53</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201239</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C53</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C53</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201241</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201242</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201243</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201244" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201244</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201245</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201246" alias="SHAH_H000019_T05_05_DLP01-A108833A-R13-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201246</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201247</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201249</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201250</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201251</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201252</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201253" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C41">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201253</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C41</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201254</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201255</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201257</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201258</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201259</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23201260</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201261</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201262" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C41">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201262</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C41</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201263</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C41</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201264</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C41</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201265</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201266</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C41</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201267</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201268</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201269</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201270</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23201272</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201280</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201281</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201282</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201283</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201284</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201285</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23201290</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX23201291</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201298" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201298</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201299</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201300</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201301</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201302</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201303</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201304</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201305</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201307" alias="SHAH_H000019_T05_05_DLP01-A108833A-R06-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201307</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R06-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201308</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C65</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201309" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201309</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C65</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201310" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C65">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201310</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C65</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201311</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201312</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201313</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201314</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C65</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201315</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201316" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201316</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201317" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201317</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201318" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201318</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201319" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201319</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201320" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201320</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201321" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201321</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201322</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201323</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201324</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201325" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201325</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201326" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201326</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201327" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201327</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201328" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201328</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R28-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201329</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201330</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C28</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201331</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201332</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201333</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201334" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201334</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C52</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201335</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201336</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201337" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201337</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201338</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201339</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201340</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201341</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201342</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201343</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201344</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201345</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201346</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201355</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201362</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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      <PRIMARY_ID>SRX23201363</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201364</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201370</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201371</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201372</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201373</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201374</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201375</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201376</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201379" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201379</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C12</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201380</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201381</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C12</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201382</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201383</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201384</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201385</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201386</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201387</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201388" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201388</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C12</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201389</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201390</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C12</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201391</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C12</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201392</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201393</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201394</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201395</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201396</PRIMARY_ID>
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    </IDENTIFIERS>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201397" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201397</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201398" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201398</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201399" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201399</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C29</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201400</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201401</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201402</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201403</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201404</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201405</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201406" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201406</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201407" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201407</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201408" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201408</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201409" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201409</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201410</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201411</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201412</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201413</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R06-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201414</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201415" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201415</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201416" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201416</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201417" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201417</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201418" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201418</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201419" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201419</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201420" alias="SHAH_H000019_T05_05_DLP01-A108833A-R26-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201420</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R26-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201421" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201421</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201422" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201422</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C60</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201423</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201424" alias="SHAH_H000019_T05_05_DLP01-A108833A-R07-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201424</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R07-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201425" alias="SHAH_H000019_T05_05_DLP01-A108833A-R14-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201425</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R14-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201426" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201426</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201427" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201427</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C36</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201428" alias="SHAH_H000019_T05_05_DLP01-A108833A-R18-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201428</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C36</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201429" alias="SHAH_H000019_T05_05_DLP01-A108833A-R28-C36">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201429</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201430</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201431</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C36</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201432</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201433" alias="SHAH_H000019_T05_05_DLP01-A108833A-R29-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201433</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R29-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R29-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201434</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R13-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R13-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201435</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201436</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201437</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201438</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201439</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201440</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201441</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201442</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201443</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201444</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201445</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201446</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201447</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201451" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201451</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201452</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C08</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201453</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C08</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201454" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C08">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201454</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C08</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201455</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C08</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201456</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201457</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R28-C08</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201458</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201459</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201460" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201460</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R20-C44</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201461</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R18-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201462</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R24-C44</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201463</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201464</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201465</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201466</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201467</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201468</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201469" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C37">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201469</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C37</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201470</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C37</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201471</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C37</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201472</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201473</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201474</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C37</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201475</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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      <PRIMARY_ID>SRX23201476</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201477</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201478" alias="SHAH_H000019_T05_05_DLP01-A108833A-R20-C32">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201478</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R20-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201479</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C32</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201480</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201481</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201482</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201483</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201484</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201487" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201487</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C10</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201488" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201488</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C10</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201489" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C10">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201489</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C10</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201490</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C10</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C10</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201491</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R24-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201492</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R07-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201493</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201494</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201495</PRIMARY_ID>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201496" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201496</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201497</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201498</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201499</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201500</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C06</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201501</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201502</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201503</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201504</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201505" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201505</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201506" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C06">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201506</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C06</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C06</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201507" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201507</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201508" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201508</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201509" alias="SHAH_H000019_T05_05_DLP01-A108833A-R08-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201509</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R08-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R08-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201510" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201510</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201511</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201513</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201514" alias="SHAH_H000019_T05_05_DLP01-A108833A-R21-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R21-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201515" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201515</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201516" alias="SHAH_H000019_T05_05_DLP01-A108833A-R17-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201516</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R17-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201517" alias="SHAH_H000019_T05_05_DLP01-A108833A-R04-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201517</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R04-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R04-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201518" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201518</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201519" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201519</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201520" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201521" alias="SHAH_H000019_T05_05_DLP01-A108833A-R12-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201521</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201522" alias="SHAH_H000019_T05_05_DLP01-A108833A-R03-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201523" alias="SHAH_H000019_T05_05_DLP01-A108833A-R05-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201523</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201524" alias="SHAH_H000019_T05_05_DLP01-A108833A-R27-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201524</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201525" alias="SHAH_H000019_T05_05_DLP01-A108833A-R23-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201525</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R23-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R23-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201526" alias="SHAH_H000019_T05_05_DLP01-A108833A-R11-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201526</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201527" alias="SHAH_H000019_T05_05_DLP01-A108833A-R30-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201527</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R30-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R30-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201528" alias="SHAH_H000019_T05_05_DLP01-A108833A-R10-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201528</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R10-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R10-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201529</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R17-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201530</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201531</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201532" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201532</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000019_T05_05_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201533" alias="SHAH_H000019_T05_05_DLP01-A108833A-R25-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201533</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R25-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R25-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201534" alias="SHAH_H000019_T05_05_DLP01-A108833A-R19-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201534</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201535" alias="SHAH_H000019_T05_05_DLP01-A108833A-R22-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201535</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R12-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R12-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201537</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R03-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R03-C55</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201539</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R14-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201540</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201541" alias="SHAH_H000019_T05_05_DLP01-A108833A-R09-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201541</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R09-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20126696" refname="SHAH_H000019_T05_05_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R09-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R05-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R05-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201543</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R27-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R27-C31</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R15-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R15-C31</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201545</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R11-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R11-C31</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R21-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201547</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201548</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201549</PRIMARY_ID>
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    </IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201550</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201551</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201552</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201553</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23201554</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201555</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <PRIMARY_ID>SRX23201556</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23201559" alias="SHAH_H000019_T05_05_DLP01-A108833A-R16-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201559</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R16-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20126696</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R16-C24</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201560</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R19-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R19-C24</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201561</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R22-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000019_T05_05_DLP01-A108833A-R22-C24</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201562</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R26-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201563</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000019_T05_05_DLP01-A108833A-R18-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201565</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000019_T05_05_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23201566</PRIMARY_ID>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298605" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298605</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298606" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298606</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298607" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298607</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298608" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298608</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298609" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298609</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298610</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298611</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298612</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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    <DESIGN>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298613</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298614" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298614</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298615" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298615</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298616" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298616</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298617" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298617</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298618" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298618</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298619</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298620</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298621</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298622</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298623" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298623</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298624" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298624</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298625" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298625</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298626" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298626</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298627</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298628</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298629</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298630</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298631</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23298632" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298632</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298633</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298634" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298634</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23298635" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298635</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298636</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298637</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298638</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298639</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298640</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23298641" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298641</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298642" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298642</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298643" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298643</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298644" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298644</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298645" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298645</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298646</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298647</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298648</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298649</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298650</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298651" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298651</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298652" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298652</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298653" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298653</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23298654" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298654</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23298655" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298655</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298656</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298657</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298658</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298659</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298660" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298660</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298661" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298661</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298662" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298662</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298663" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298663</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298664" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298664</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298665</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298666</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298668</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298670</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298672" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298674" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298674</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298676" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298676</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298678" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298678</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298680" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298680</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298682" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298682</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298684" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298684</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298686</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298688</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298690" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298690</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298692" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298692</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298694" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298694</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298696" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298696</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298698" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298698</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298700" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298700</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298702" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298702</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298704" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298704</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298706" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298706</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298708" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298710" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298712" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298714" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298714</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298716" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298718" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298720" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298722" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298723" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298723</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298725" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298727" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298729" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298729</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298731" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298731</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298733" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298733</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298735" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298737" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298739" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298741" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298741</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298743" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298743</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298745" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298747" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298747</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298749" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298749</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298751" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298751</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298753" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298755" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298755</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298757" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298757</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298759" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298759</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298761" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298761</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298763" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298763</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298765" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298765</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298767" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298767</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298769" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298769</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298771" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298771</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298773" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298773</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298775" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298775</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298777</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298779" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298781" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298781</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298783" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298783</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298785" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298785</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298787" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298787</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298789" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298791" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298791</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298793" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298793</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298795" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298795</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298797" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298799" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298799</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298801" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298801</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298803" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298803</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298805" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298807" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298809" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298811" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298811</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298813" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298813</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298815" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298817" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298819" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298821" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298823" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298825" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298827" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298829" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298831" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298833" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298835" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298837" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298839" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298841" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298843" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298845" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298845</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298847" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298847</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298849" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298849</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298851" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298851</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298853" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298855" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298857" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298857</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298859" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298859</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298861" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298861</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298863" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298863</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298865" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298865</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298867" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298867</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298869" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298869</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298871" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298871</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298873" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298873</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298875" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298875</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298877" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298877</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298879" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298879</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298881" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298881</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298883" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298883</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298885" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298885</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298887" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298887</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298889" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298889</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298891" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298891</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298893" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298893</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298895" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298895</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298897" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298897</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298899" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298899</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298901" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298901</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298903" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298903</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298905" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298905</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298907" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298907</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298909" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298909</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298911" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298911</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298913" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298913</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298915" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298915</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298917" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298917</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298919" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298919</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298921" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298921</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298923" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298923</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298925" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298925</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298927" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298927</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298929" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298929</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298931" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298931</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298933" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298933</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298935" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298935</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298937" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298937</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298939" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298939</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298941" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298941</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298943" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298943</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298945" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298945</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298947" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298947</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298949" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298949</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298951" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298951</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298953" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298953</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298955" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298955</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298957" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298957</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298959" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298959</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298961" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298961</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298963" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298963</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298965" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298965</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298967" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298967</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298969" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298969</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298971" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298971</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298973" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298973</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298975" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298975</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298977" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298977</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298979" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298979</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298981" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298981</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298983" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298983</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298985" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298985</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298987" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298987</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298989" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298989</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298991" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298991</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298993" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298993</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298995" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298995</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298997" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298997</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23298999" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23298999</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299001" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299001</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299003" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299003</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299005" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299005</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299007" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299007</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299009" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299009</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299011" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299011</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299013" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299013</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299015" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299015</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299017" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299017</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299019" alias="SHAH_H000340_T01_04_DLP01-128673A-R03-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299019</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R03-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R03-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299021" alias="SHAH_H000340_T01_04_DLP01-128673A-R04-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299021</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R04-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R04-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299023" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299023</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299025" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299025</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299027" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299027</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299029" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299029</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299031" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299031</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299033" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299033</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299035" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299035</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299037" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299037</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299039" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299039</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299041" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299041</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299043" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299043</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299045" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299045</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299047</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299049" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299049</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299051" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299051</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299053" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299053</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299055" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299055</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299057" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299057</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299059" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299059</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299061</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299063" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299063</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299065</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299067" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299067</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299069" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299069</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299071" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299071</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299073" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299073</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299075" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299075</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299077" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299077</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299079" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299079</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299081" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299081</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299083</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299085" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299085</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299087" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299087</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299089" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299089</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299091" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299091</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299093" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299093</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299095" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299095</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299097" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299097</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299099" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299099</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299101</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299103" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299103</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299105" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299105</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299107" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299107</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299109" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299109</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299111" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299111</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299113" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299113</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299115</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299117" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299117</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299119</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299121" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299121</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299123" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299123</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299125" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299125</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299127" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299127</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299129" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299129</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299131" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299131</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299133" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299133</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299135</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299137</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299139" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299139</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299141" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299141</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299143" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299143</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299145" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299145</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299147" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299147</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299149" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299149</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299151" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299151</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299153" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299153</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299155</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299157" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299157</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299159" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299159</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299161" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299161</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299163" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299163</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299165" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299165</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299167" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299167</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299169</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299171</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299173</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299175" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299175</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299177" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299177</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299179" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299179</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299181" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299181</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299183" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299183</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299185</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299187</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299189</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299191</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299193" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299193</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299195" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299195</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299197" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299197</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299199" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299199</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299202" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299202</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299204" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299204</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299206" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299206</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299208" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299208</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299210</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299212" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299212</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299214" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299214</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299216" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299216</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299218" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299220" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299222" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299226</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299228</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299230" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299230</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299232" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299232</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299234" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299234</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299236" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299236</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299238" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299240" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299242" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299242</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299244" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299244</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299246</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299248" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299250" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299250</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299252" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299252</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299254" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299254</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299256" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299258" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299258</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299260" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299260</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299262</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299264</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299266" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299266</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299268" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299268</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299270" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299270</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299272" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299272</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299274" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299274</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299276" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299276</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299278</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299280</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299282</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299284" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299284</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299286" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299286</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299288" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299288</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299290" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299290</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299292" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299292</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299294" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299294</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299296" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299296</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299298</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299300</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299302" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299302</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299304" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299304</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299306" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299306</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299308" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299308</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299310" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299310</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299312" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299312</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299314</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299316</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299318</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299320" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299320</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299322" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299322</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299324" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299324</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299326" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299326</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299328" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299328</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299330" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299330</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299332</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299334</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299336</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299338" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299338</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299340" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299340</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299342" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299342</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299344" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299344</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299346" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299346</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299348</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299350</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299352</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C62</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299354</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299356" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299356</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299358" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299358</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299360" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299360</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299362" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299362</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299364" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299364</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299366" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299366</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299368</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299370</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C20</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299372</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299374" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299374</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299376" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299376</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299378" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299378</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299380" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299380</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299382" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299382</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299384" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299384</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299386</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299388</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299390</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299392" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299392</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299394" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299394</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299396" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299396</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299398" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299398</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299400" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299400</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299402" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299402</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299404" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299404</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299406" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299406</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299408</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299410" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299410</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299412" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299412</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299414" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299414</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299416" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299416</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299418" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299418</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299420" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299420</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299422" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299422</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C57</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299424" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299424</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299426" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299426</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299428" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299428</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299430" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299430</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299432" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299432</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299434" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299434</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299436" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299436</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299438" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299438</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299440" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299440</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299442</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299444</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299446" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299446</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299448" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299448</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299450" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299450</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299452" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299452</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299454" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299454</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299456</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299458</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299460</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C45</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299462</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299464" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299464</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299466" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299466</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299468" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299468</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299470" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299470</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299472" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299472</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299474" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299474</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C45</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299476</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299478</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299480</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299482" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299482</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299484" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299484</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299486" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299486</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299488" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299488</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299490" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299490</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299492" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299492</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299494</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299496</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299498</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299500" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299500</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299502" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299502</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299504" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299504</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299506" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299506</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299508" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299508</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299510" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299510</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299512" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299514" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299516</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299518" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299518</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299520" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299522" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299524" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299524</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299526" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299526</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299528" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299528</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299530" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299530</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299532" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299532</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299534" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299534</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299536" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299538" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299540" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299540</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299542" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299544" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299546" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299548" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299548</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299550" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299550</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299552" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299552</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299554" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299554</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299556" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299556</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299558" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299558</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299560" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299560</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299562" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299562</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299564" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C54</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299566</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299568</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299570</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299572" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299572</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299574" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299574</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299576" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299576</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299578" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299578</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299580" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299580</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299582" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299582</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299584</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299586</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299588</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299590" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299590</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299592" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299592</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299594" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299594</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299596" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299596</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299598" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299598</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299600" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299600</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299602</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299604</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C12</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299606</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299608" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299608</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299610" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299610</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299612" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299612</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299614" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299614</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299616" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299616</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299618" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299618</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299620" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299620</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299622" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299622</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299624" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299624</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299626" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299626</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299628" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299628</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299630" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299630</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299632" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299632</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299634" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299634</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299636" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299636</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299638" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299638</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299640" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299640</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299642" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299642</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299644" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299644</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299646" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299646</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299648" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299648</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299650" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299650</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299652" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299652</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299654" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299654</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299656</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299658</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299660</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299662" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299662</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299664" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299664</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299666" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299666</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299668" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299668</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299670" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299670</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299672" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299674</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299676</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299678</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299680" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299680</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299682" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299682</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299684" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299684</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299686" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299686</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299688" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299688</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299690" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299690</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299692</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299694</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C20</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299696</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299698" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299698</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299700" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299700</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299702" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299702</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299704" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299704</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299706" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299706</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299708" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C46</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299710" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299714</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299716" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299718" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299720" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299722" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299724" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299724</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299726" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299728" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299728</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299730" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299730</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299732</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299734" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299736" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299738" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299738</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299740" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299740</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299742" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299742</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299744" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299746" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299746</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299748" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299748</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299750" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299750</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299752" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299754" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299754</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299756" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299756</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299758" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299758</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299760" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299760</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299766</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C47</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299768</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299770" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299770</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299772" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299772</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299774" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299774</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299776" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299776</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299778" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299778</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299780" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299780</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299782</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299784</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299786</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299788" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299788</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299790" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299792" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299792</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299794" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299794</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299796" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299796</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299798" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299800</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299803</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C05</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299807" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299809" alias="SHAH_H000340_T03_03_DLP01-128689A-R03-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R03-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R03-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299811" alias="SHAH_H000340_T03_03_DLP01-128689A-R41-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299811</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R41-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R41-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299813" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299813</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299815" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299817" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C05</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299825" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299827" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299829" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299831" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299833" alias="SHAH_H000340_T03_03_DLP01-128689A-R03-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R03-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R03-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299835" alias="SHAH_H000340_T03_03_DLP01-128689A-R41-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R41-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R41-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299837" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299839" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23299841" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299843" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299845" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299845</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299847" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299847</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299849" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299849</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299851" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299851</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23299853" alias="SHAH_H000340_T03_03_DLP01-128689A-R04-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R04-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R04-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23299855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300644</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300645</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300646" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300646</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300647" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300647</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300648" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300648</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300649" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300649</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300650" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300650</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300651</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300652</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300654</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300655</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300656</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C50</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300657</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300658</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300659</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23300660</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300663</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300664" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300664</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300665" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300665</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300666" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300666</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300667" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300667</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300668" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300668</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300669</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300670</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300671</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300673" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300673</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300674" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300674</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300675" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300675</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300676" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300676</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300677" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300677</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300678</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C51</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300679</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300680</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300681</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300682" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300682</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300683" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300683</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300684" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300684</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300685" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300685</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300686" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300686</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300687</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300688</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300689</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300690</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300691" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300691</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300692" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300692</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300693" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300693</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300694" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300694</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300695" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300695</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300696</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300697</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300698</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C52</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300699</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300700" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300700</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300701" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300701</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300702" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300702</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300703" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300703</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300704" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300704</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300705</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300706</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300707</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300709" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300709</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300710" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300711" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300711</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300712" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300713" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300713</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300714</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300715</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300716</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300717</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300718" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300719" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300719</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300720" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300721" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300721</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300722" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300723" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300723</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300724</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300727" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300728" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300728</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300729" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300729</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300730" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300730</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300731" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300731</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300732</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300733</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C50</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300734</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C51</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300736" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300737" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300738" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300738</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300739" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300740" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300740</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300741</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300742</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300743</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300745" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300746" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300746</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300747" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300747</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300748" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300748</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300749" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300749</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300750</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300751</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C28</LIBRARY_NAME>
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        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300754" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300754</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300755" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300755</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300756" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300756</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300757" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300757</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300758" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300758</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300759</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300760</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300761</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C58</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300763" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300763</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300764" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300765" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300765</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300766" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300766</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300767" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300767</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300768</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300769</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300770</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300771</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300772" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300772</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300773" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300773</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300774" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300774</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300775" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300775</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300776" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300776</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300777</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300778</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300780</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300781" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300781</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300782" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300782</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300783" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300783</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300784" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300784</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300785" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300785</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300786</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300787</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300788</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300790" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300791" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300791</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300792" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300792</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300793" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300793</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300794" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300794</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300795" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300795</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300796</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300799" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300799</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300800" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300800</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300801" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300801</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300802" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300802</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300803" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300803</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300804" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300804</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300808" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300808</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300809" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300810" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300810</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300811" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300811</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300812" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300812</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300813</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C59</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300814</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300815</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300816</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R10-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R10-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300817" alias="SHAH_H000340_T01_04_DLP01-128673A-R11-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R11-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R11-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300818" alias="SHAH_H000340_T01_04_DLP01-128673A-R12-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300818</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R12-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R12-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300819" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300820" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300820</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300821" alias="SHAH_H000340_T01_04_DLP01-128673A-R05-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R05-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R05-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300822</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R06-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R07-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300824</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R09-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R09-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300826" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300826</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300827" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300828" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300828</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300829" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300830" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300830</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23300831" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C17</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300832</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300834</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300835" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300836" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300836</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300837" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300838" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300838</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300839" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300840</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300842</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300844" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300844</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300845" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300845</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300846" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300846</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300847</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300848" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300848</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300849</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300850</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300851</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300852</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300853" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300854" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300854</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300855" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300856" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300856</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300857" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300857</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300858</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300859</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300860</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300861</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300862" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300862</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300863" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300863</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300864" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300864</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300865</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C27</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23300866" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300866</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C28</LIBRARY_NAME>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300867</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300868</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300870</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300871" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300871</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300872" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300872</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300873" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300873</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300874</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23300875" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300875</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300876</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300877</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300878</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300879</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300880" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300880</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300881" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300881</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300882" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300882</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300883" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300883</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300884" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300884</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300885</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300886</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C24</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300887</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C25</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300888</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300889" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300889</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300890" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300890</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300891" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300891</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23300892" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300892</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23300893" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300893</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C31</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300894</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300895</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300896</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300897</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300898" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300898</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300899" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300899</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300900" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300900</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300901" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300901</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300902" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300902</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300903</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300904</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300905</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300906</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300907" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300907</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300908" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300908</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300909" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300909</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300910" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300910</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300911" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300911</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300912" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300912</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300913</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300914</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300915</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300916" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300916</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300917" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300917</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300918" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300918</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300919" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300919</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300920" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300920</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300921</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300922</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300923</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300924</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300925" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300925</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300926" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300926</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300927" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300927</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300928" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300928</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300929" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300929</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C54</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300930</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300931</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300933</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300934" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300934</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300935" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300935</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300936" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300936</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300937" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300937</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300938" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300938</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    <PLATFORM>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300939</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300940</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300941</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300942</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300943" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300943</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300944" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300944</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300945" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300945</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300946" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300946</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300947" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300947</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300948</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300949</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300950</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300951</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300952" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300952</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300953" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300953</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300954" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300954</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300955" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300955</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300956" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300956</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C57</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300957</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300958</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300959</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300960</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300961" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300961</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300962" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300962</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300963" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300963</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300964" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300964</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300965" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300965</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300966</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300967</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300968</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300969</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300970" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300970</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300971" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300971</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300972" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300972</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300973" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300973</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300974" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300974</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300975</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300976</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300977</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300978</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300979" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300979</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300980" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300980</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300981" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300981</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300982</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300983</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C60</LIBRARY_NAME>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300984</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300985</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
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    <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300987</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300988" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300988</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300989" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300989</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300990" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300990</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300991" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300991</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300992" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300992</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300993</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300994</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300995</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C21</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300996</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300997" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300997</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300998" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300998</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23300999" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23300999</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301000" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301000</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301001" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301001</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301002</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C20</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301003</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301004</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301005</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301006" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301006</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301007" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301007</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301008" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301008</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301009" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301009</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301010" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301010</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301011" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301011</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301012" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301012</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301013" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301013</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301014</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301015" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301015</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301016" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301016</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301017" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301017</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301018" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301018</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301019" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301019</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301020" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301020</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301021" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301021</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301022" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301022</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301023</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301024" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301024</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301025" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301025</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301026" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301026</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301027" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301027</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301028" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301028</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301029" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301029</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301030" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301030</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301031" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301031</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301032</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301033" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301033</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301034" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301034</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301035" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301035</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301036" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301036</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301037" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301037</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301038" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301038</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301039" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301039</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301040" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301040</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301041</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301042" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301042</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301043" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301043</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301044" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301044</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301045" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301045</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301046" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301046</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301047</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C18</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301048</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C19</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301049</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C20</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C20</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301050</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301051" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301051</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301052" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301052</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301053" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301053</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301054" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301054</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301055" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301055</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301056</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301057</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301058</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C29</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301059</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301060" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301060</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301061" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301061</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301062" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301062</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301063" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301063</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301064" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301064</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23301065" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301065</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301066</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301067</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C58</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301068</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301069" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301069</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301070" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301070</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301071" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301071</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301072" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301072</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301073" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301073</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301074" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301074</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301075</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301076</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301077</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301078" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301078</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301079" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301079</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301080" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301080</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301081" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301081</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301082" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301082</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301083</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301084</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301085</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301086</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301087" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301087</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301088" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301088</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301089" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301089</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301090" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301090</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301091" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301091</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301092" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301092</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301093" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301093</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301094</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301095</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301096" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301096</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301097" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301097</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301098" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301098</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301099" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301099</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301100" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301100</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301101</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301102</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C15</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301103</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C16</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301104</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301105" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301105</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301106" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301106</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301107" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301107</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301108" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301108</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301109" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301109</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301110</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301111</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C50</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301112</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C51</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301113</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301114" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301114</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301115" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301115</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301116" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301116</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301117" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301117</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301118" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301118</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301119</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301120</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301121</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301122</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301123" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301123</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301124" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301124</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301125" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301125</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301126" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301126</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301127" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301127</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301128</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301129</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301131</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301132" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301132</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301133" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301133</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301134" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301134</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301135" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301135</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301136" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301136</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301137</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301138</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301139</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301140</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301141" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301141</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301142" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301142</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301143" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301143</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301144" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301144</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301145</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301146</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301147</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23301148</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301149</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301150" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301150</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301151" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301151</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301152" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301152</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301153" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301153</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301154" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301154</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301155</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301156</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23301157</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301158</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301159" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301159</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301160" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301160</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301161" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301161</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301162" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301162</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301163" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301163</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301164</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301165</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301166</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301167</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301168" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301168</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301169</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
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          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301170</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301171</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301172</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301173</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301174</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301176</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301177" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301177</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301178" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301178</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301179" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301179</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301180" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301180</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301181" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301181</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301182</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301183</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301184</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301185</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C58</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301186</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301187</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C60</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301188</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301189</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301190</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23301191</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23301192</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301194</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301195" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301195</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301196" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301196</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301197" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301197</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301198" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301198</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301199" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301199</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301200" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301200</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301201</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301202</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301203</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301204" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301204</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301205" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301205</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301206" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301206</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301207" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301207</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301208" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301208</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301209</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301210</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301211</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C13</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301212</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301213" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301213</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301214" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301214</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301215" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301215</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301216" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301216</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301217" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301217</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301218" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301219" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301219</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301220" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301221" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301221</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301222" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301223" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301223</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301224" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301225" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301225</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301226" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301226</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301227</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301228</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301229</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C58</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301230</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301231" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301231</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301232" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301232</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301233" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301233</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301234" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301234</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301235" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301235</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301236" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301236</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301237</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C60</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301239</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301240" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301241" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301241</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301242" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301242</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301243" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301243</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301244" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301244</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301245" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301245</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301246</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301247</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301249" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301249</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301250" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301250</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301251" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301251</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301252" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301252</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301253" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301253</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301254</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301255</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301257</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301259" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301259</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301261" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301261</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301263" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301263</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301265" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301265</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301267" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301267</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301268" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301268</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301270" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301270</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301272</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301274</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301276" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301276</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301278" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301278</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301280" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301280</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301282" alias="SHAH_H000340_T03_03_DLP01-128689A-R10-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301282</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R10-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R10-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301283" alias="SHAH_H000340_T03_03_DLP01-128689A-R11-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301283</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R11-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R11-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301285</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R12-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R12-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301287</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301288</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C05</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301290</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301292" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301292</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301293" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301293</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301295" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301295</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301297" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301297</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301299" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301299</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301301</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301303</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301305</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C05</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C05</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301307</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301309" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301309</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301311" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301311</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301312" alias="SHAH_H000340_T03_03_DLP01-128689A-R04-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301312</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R04-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R04-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301314" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301314</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301315" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301315</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301317" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301317</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301318" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301318</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301320</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C05</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301321</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301322" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301322</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301323" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301323</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301324" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301324</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301325" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301325</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301326" alias="SHAH_H000340_T03_03_DLP01-128689A-R05-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301326</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R05-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R05-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301327</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301328</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301329</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301330</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301331" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301331</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301332" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301332</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
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          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23301333" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301333</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301334</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C03</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301335</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301336</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301337</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301339</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301340" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301340</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301341" alias="SHAH_H000340_T03_03_DLP01-128689A-R62-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301341</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R62-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R62-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23301342" alias="SHAH_H000340_T03_03_DLP01-128689A-R63-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301342</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R63-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R63-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23301343" alias="SHAH_H000340_T03_03_DLP01-128689A-R64-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301343</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R64-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R64-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23301344" alias="SHAH_H000340_T03_03_DLP01-128689A-R65-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23301344</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R65-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R65-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302072</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302073</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302074</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302075</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302076" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302076</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302077" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302077</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302078" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302078</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302079" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302079</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302080" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302080</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302081</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302082</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C59</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302083</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302084</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302085" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302085</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302086" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302086</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302087" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302087</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302088" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302088</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302089" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302089</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302090</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302091</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C61</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302092</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302093</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302094" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302094</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302095" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302095</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302096" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302096</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302097" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302097</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302098" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302098</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302099" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302099</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302100</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302101</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302102</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302103" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302103</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302104" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302104</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302105" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302105</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302106" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302106</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302107" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302107</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302108" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302108</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302109" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302109</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302110" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302110</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302111</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302112" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302112</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302113" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302113</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302114" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302114</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302115" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302115</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302116" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302116</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302117" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302117</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302118" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302118</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302119" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302119</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302120</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302121" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302121</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302122" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302122</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302123" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302123</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302124" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302124</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302125" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302125</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302126" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302126</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302127</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302128</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302129</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302130" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302130</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302131" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302131</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302132" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302132</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302133" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302133</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302134" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302134</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302135</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302136</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302137</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302138</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302139" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302139</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302140" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302140</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302141" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302141</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302142" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302142</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302143" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302143</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302144" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302144</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302145</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302146</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302147</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302148" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302148</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302149" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302149</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302150" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302150</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302151" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302151</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302152" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302152</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302153" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302153</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302154" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302154</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302155</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302156</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302157" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302157</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302158" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302158</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302159" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302159</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302160" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302160</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302161" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302161</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302162" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302162</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302163" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302163</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C44</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302164</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302165</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302166" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302166</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302167" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302167</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302168" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302168</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302169" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302169</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302170" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302170</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302171" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302171</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302172</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C13</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302173</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C14</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302174</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302175" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302175</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302176" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302176</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302177" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302177</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302178" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302178</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302179" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302179</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302180" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302180</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302181" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302181</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302182" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302182</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302183</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302184" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302184</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302185" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302185</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302186" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302186</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302187" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302187</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302188" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302188</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302189</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C49</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302190</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302191</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302192</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302193" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302193</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302194" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302194</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302195" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302195</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302196" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302196</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302197" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302197</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302198" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302198</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302199" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302199</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302200" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302200</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302201</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302202" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302202</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302203" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302203</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302204" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302204</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302205" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302205</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302206" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302206</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302207" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302207</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302208</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C28</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302209</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302210</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302211" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302211</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302212" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302212</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302213" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302213</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302214" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302214</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302215" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302215</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302216" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302216</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302217</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C57</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302219</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302220" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302221" alias="SHAH_H000340_T01_04_DLP01-128673A-R29-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302221</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302222" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302223" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302223</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302224" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302225" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302225</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302226</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302227</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302228</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302229" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302229</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302230" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302230</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302231" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302231</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302232" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302232</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302233" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302233</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302234</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302235</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C44</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302236</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302237</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302238" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302239" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302239</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302240" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302241" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302241</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302242" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302242</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302243" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302243</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302244</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C54</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302245</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302246</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302247" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302247</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302248" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302249" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302249</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302250" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302250</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302251" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302251</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302252</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C05</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302253</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C05</LIBRARY_NAME>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302254</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302255</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302256" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302257" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302257</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302258" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302258</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302259" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302259</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302260" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302260</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302261</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302262</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C05</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302263</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302264</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302265" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302265</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302266" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302266</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302267" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302267</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302268" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302268</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302269" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302269</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302270</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302271</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302272</PRIMARY_ID>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302273</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302274" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302274</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302275" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302275</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302276" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302276</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302277" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302277</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302278" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302278</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302279</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302280</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302281</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302282</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302283" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302283</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302284" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302284</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302285" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302285</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302286" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302286</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302287" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302287</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302288</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302289</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302290</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302291</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302292" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302292</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302293" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302293</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302294" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302294</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302295" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302295</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302296" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302296</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302297</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302298</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302299</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302300</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302301" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302301</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302302" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302302</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302303" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302303</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302304" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302304</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302305" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302305</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302306</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302307</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C52</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302308</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302309</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302310" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302310</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302311" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302311</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302312" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302312</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302313" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302313</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302314" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302314</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302315</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302316</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C19</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302317</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C20</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302318</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302319" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302319</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302320" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302320</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302321" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302321</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302322" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302322</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302323" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302323</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302324" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302324</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302325</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C28</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302326</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302327</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302328" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302328</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302329" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302329</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302330" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302330</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302331" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302331</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302332" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302332</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302333</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302334</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302335</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C57</LIBRARY_NAME>
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          <PAIRED/>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302336</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302337" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302337</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302338" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302338</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302339" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302339</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302340" alias="SHAH_H000340_T03_03_DLP01-128689A-R19-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302340</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R19-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R19-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302341" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302341</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302342</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302343</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302344</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302345</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302346" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302346</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302347" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302347</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302348" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302348</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302349" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302349</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302350" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302350</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302351</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302352</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302353</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302354</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302355" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302355</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302356" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302356</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302357" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302357</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302358" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302358</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302359" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302359</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302360</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302361</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302362</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302363</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302364" alias="SHAH_H000340_T03_03_DLP01-128689A-R22-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302364</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302365" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302365</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302366" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302366</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302367" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302367</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302368" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302368</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302369</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302370</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302371</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302372</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302373" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302373</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302374" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302374</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302375" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302375</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302376" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302376</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302377" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302377</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302378</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302379</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <PRIMARY_ID>SRX23302380</PRIMARY_ID>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302381</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302382" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302382</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302383" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302383</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302384" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302384</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302385" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302385</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302386" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302386</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302387</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302388</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302389</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302390</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302391" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302391</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302392" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302392</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302393" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302393</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302394" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302394</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302395" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302395</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C18</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302396</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302397</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C20</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302398</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302399</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302400" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302400</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302401" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302401</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302402" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302402</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302403" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302403</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302404" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302404</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302405</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302406</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302407</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C30</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302408</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302409" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302409</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302410" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302410</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302411" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302411</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302412" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302412</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302413" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302413</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302414</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302415</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302416</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C58</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302417</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302418" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302418</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302419" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302419</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302420" alias="SHAH_H000340_T03_03_DLP01-128689A-R27-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302420</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R27-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R27-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302421" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302421</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302422" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302422</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302423" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302423</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302424</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C23</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302425</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302426</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302427" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302427</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302428" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302428</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302429" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302429</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302430" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302430</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302431" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302431</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302432</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302433</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C42</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302434</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C43</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302435</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302436" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302436</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302437" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302437</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302438" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302438</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302439" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302439</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302440" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302440</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302441</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302442</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302443</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302444</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302445" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302445</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302446" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302446</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302447" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302447</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302448" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302448</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302449" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302449</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302450</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302451</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302452</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302453</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302454" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302454</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302455" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302455</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302456" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302456</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302457" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302457</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302458" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302458</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302459</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302460</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302461</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302462</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302463" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302463</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302464" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302464</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302465" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302465</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302466" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302466</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302467" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302467</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302468</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302469</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302470</PRIMARY_ID>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302471</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302472" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302472</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302473" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302473</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302474" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302474</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302475" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302475</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302476" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302476</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302477</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302478</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302479</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302480</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302481" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302481</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302482" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302482</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C57</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302483" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302483</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302484" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302484</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302485</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C60</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302486</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302487</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302488</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302489</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302490" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302490</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302491" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302491</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302492" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302492</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302493" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302493</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302494" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302494</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302495</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C24</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302496</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C25</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302497</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C26</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302498</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302499" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302499</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302500" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302500</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302501" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302501</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302502" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302502</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302503" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302503</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C42</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302504</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302505</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302506</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C14</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302507</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302508" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302508</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302509" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302509</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302510" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302510</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302511" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302511</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302512" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302513</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C22</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302515</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302516</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302517" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302517</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302518" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302518</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302519" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302519</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302520" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302521" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302521</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302523</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302524</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302525</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302526" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302526</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302527" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302527</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302528" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302528</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302529" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302529</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302530" alias="SHAH_H000340_T03_03_DLP01-128689A-R56-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302530</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R56-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302531</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302532</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R56-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302533</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302534</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302535" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302535</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302536" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302537" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302537</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302538" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302539" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302539</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302540</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C20</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302541</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C21</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302543</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302544" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302545" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302545</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302546" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302547" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302547</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302548" alias="SHAH_H000340_T03_03_DLP01-128689A-R59-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302548</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302549</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302550</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R59-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R59-C30</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302551</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302552</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302553" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302553</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302554" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302554</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302555" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302555</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302556" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302556</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302557" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302557</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302558</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302559</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C42</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302560</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302561</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302562" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302562</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302563" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302563</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302564" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302565" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302565</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302566" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302566</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302567</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302568</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R62-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302569</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302570</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R64-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R64-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302571" alias="SHAH_H000340_T03_03_DLP01-128689A-R65-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302571</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R65-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R65-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302572" alias="SHAH_H000340_T03_03_DLP01-128689A-R66-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302572</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R66-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R66-C05</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302573" alias="SHAH_H000340_T03_03_DLP01-128689A-R67-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302573</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R67-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R67-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302574</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R68-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R68-C05</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302575" alias="SHAH_H000340_T03_03_DLP01-128689A-R69-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302575</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R69-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R69-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302576</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R06-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302577</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R70-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302579</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R08-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R08-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302580" alias="SHAH_H000340_T03_03_DLP01-128689A-R09-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302580</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R09-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R09-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302581</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R10-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R10-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302582</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R11-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R11-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302583</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R12-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302584</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R66-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302585</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302586</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302588</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R06-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R06-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302589" alias="SHAH_H000340_T03_03_DLP01-128689A-R70-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302589</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R70-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R70-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302590" alias="SHAH_H000340_T03_03_DLP01-128689A-R07-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302590</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R07-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R07-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302591" alias="SHAH_H000340_T03_03_DLP01-128689A-R08-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302591</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R08-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R08-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23302592" alias="SHAH_H000340_T03_03_DLP01-128689A-R09-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23302592</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R09-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R09-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303190" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303190</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303191</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303192</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303193</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303194</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303195" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303195</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303196" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303196</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303197" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303197</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303198" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303198</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303199" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303199</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303200" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303200</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303201" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303201</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303202" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303202</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303203" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303203</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303204" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303204</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303205" alias="SHAH_H000340_T01_04_DLP01-128673A-R14-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303205</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303206" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303206</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303207" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303207</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303208" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303208</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303209" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303209</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303210" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303210</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303211</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303212</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303213" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303213</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303214" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303214</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303215" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303215</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303216" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303216</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303217" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303217</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303218</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303219</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303220</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303221</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303222" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303222</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303223" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303223</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303224" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303224</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303225" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303225</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303226" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303226</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303227</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303228</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C49</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303229</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303230</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303231" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303231</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303232" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303232</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303233" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303233</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303234" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303234</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303235" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303235</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303236</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303237</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C59</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303238</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C52</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303239</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303240" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303240</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303241" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303241</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303242" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303242</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303243" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303243</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303244" alias="SHAH_H000340_T01_04_DLP01-128673A-R18-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303244</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303245</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C60</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303246</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R18-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R18-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303247</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303248</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303249" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303249</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303250" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303250</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303251" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303251</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303252" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303252</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303253" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303253</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303254" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303254</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303255" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303255</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303256" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303256</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303257</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303258" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303258</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303259" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303259</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303260" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303260</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303261" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303261</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303262" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303262</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303263" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303263</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303264</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303265</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303266</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303267" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303267</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303268" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303268</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303269" alias="SHAH_H000340_T01_04_DLP01-128673A-R19-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303269</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R19-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R19-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303270" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303270</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303271" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303271</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303272</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303273</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303274</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303275</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303276" alias="SHAH_H000340_T01_04_DLP01-128673A-R20-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303276</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R20-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R20-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303277" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303277</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303278" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303278</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303279" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303279</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303280" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303280</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303281</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303282</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C17</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303283</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303284</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303285" alias="SHAH_H000340_T01_04_DLP01-128673A-R21-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303285</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R21-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R21-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303286" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303286</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303287" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303287</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303288" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303288</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303289" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303289</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303290</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303291</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303292</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303293</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303294" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303294</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303295" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303295</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303296" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303296</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303297" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303297</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303298" alias="SHAH_H000340_T01_04_DLP01-128673A-R22-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303298</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303299</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303300</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R22-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303301</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R22-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303302</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303303" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303303</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303304" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303304</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303305" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303305</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303306" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303306</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303307" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303307</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303308" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303308</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303309" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303309</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303310</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303311</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303312" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303312</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303313" alias="SHAH_H000340_T01_04_DLP01-128673A-R23-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303313</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R23-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R23-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303314" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303314</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303315" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303315</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303316" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303316</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303317" alias="SHAH_H000340_T01_04_DLP01-128673A-R24-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303317</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R24-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R24-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303318</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303319</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303320</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303321" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303321</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303322" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303322</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303323" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303323</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303324" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303324</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303325" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303325</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303326" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303326</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303327" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303327</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303328" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303328</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303329</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303330" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303330</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303331" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303331</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303332" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303332</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303333" alias="SHAH_H000340_T01_04_DLP01-128673A-R25-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303333</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R25-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R25-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303334" alias="SHAH_H000340_T01_04_DLP01-128673A-R26-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303334</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R26-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R26-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303335" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303335</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303336</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C13</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303337</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303338</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303339" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303339</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303340" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303340</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303341" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303341</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303342" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303342</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303343" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303343</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303344</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303345</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303346</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303347</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303348" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303348</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303349" alias="SHAH_H000340_T01_04_DLP01-128673A-R27-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303349</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R27-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R27-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303350" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303350</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303351" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303351</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303352" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303352</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303353</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303354</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303355</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C51</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303356</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303357" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303357</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303358" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303358</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303359" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303359</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303360" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303360</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303361" alias="SHAH_H000340_T01_04_DLP01-128673A-R28-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303361</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303362</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303363</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R28-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R28-C60</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303364</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303365</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R29-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R29-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303366" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303366</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303367" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303367</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303368" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303368</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303369" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303369</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303370" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303370</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303371</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303372</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C28</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303373</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303374</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303375" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303375</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303376" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303376</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303377" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303377</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303378" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303378</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303379" alias="SHAH_H000340_T01_04_DLP01-128673A-R30-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303379</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303380</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303381</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R30-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R30-C47</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303382</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C58</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303383</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303384" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303384</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303385" alias="SHAH_H000340_T01_04_DLP01-128673A-R31-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303385</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R31-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303386" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303386</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303387" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303387</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303388" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303388</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303389</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303390</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303391</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303392</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303393" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303393</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303394" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303394</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303395" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303395</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303396" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303396</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303397" alias="SHAH_H000340_T01_04_DLP01-128673A-R32-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303397</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R32-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R32-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303398</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R31-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303399</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R03-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R03-C05</LIBRARY_NAME>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303400</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R04-C05</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303401</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R05-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R05-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303402" alias="SHAH_H000340_T01_04_DLP01-128673A-R06-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303402</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R06-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R06-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303403" alias="SHAH_H000340_T01_04_DLP01-128673A-R07-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303403</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R07-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R07-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303404" alias="SHAH_H000340_T01_04_DLP01-128673A-R08-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303404</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R08-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R08-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303405" alias="SHAH_H000340_T01_04_DLP01-128673A-R09-C05">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303405</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R09-C05</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R09-C05</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303406" alias="SHAH_H000340_T01_04_DLP01-128673A-R10-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303406</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R10-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R10-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303407" alias="SHAH_H000340_T01_04_DLP01-128673A-R11-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303407</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R11-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R11-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303408" alias="SHAH_H000340_T01_04_DLP01-128673A-R12-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303408</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R12-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R12-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303409" alias="SHAH_H000340_T01_04_DLP01-128673A-R13-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303409</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R13-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R13-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303410</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R14-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R14-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303411" alias="SHAH_H000340_T01_04_DLP01-128673A-R15-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303411</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R15-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R15-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303412" alias="SHAH_H000340_T01_04_DLP01-128673A-R16-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303412</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R16-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R16-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303413" alias="SHAH_H000340_T01_04_DLP01-128673A-R17-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303413</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T01_04_DLP01-128673A-R17-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T01_04_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180758" refname="SHAH_H000340_T01_04_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180758</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T01_04_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T01_04_DLP01-128673A-R17-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303414" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303414</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303415" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303415</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303416" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303416</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C51</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303417</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C52</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303418</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303419</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303420" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303420</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303421" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303421</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303422" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303422</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303423" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303423</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303424" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303424</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303425</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303426</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303427</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303428</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303429" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303429</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303430" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303430</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303431" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303431</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303432" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303432</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303433" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303433</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303434</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303435</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C28</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303436</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C29</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303437</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303438" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303438</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303439" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303439</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303440" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303440</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303441" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303441</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303442" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303442</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303443</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303444</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303445</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303446</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303447" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303447</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303448" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303448</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303449" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303449</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303450" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303450</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303451" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303451</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C12</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303452</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303453</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303454</PRIMARY_ID>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303455</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303456" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303456</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303457" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303457</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303458" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303458</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303459" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303459</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303460" alias="SHAH_H000340_T03_03_DLP01-128689A-R17-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303460</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R17-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303461</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303462</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303463</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303464</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303465" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303465</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303466" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303466</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303467" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303467</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303468</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C47</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303469" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303469</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C48</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303470</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303471</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303472</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303473</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303474" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303474</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303475" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303475</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303476" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303476</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303477" alias="SHAH_H000340_T03_03_DLP01-128689A-R18-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303477</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R18-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303478" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303478</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303479</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303480</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303481</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303482</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303483" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303483</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303484" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303484</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303485" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303485</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303486" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303486</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303487" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303487</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303488</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303489</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C26</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303490</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C27</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303491</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303492" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303492</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303493" alias="SHAH_H000340_T03_03_DLP01-128689A-R20-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303493</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303494" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303494</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303495" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303495</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303496" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303496</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303497</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303498</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303499</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303500</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303501" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303501</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303502" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303502</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303503" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303503</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303504" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303504</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303505" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303505</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C61</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303506</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303507</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303508</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303509</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303510" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303510</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303511" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303511</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303512" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303512</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303513" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303513</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303514" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303514</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303515</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303516</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C29</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303517</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303518</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303519" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303519</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303520" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303520</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303521" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303521</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303522" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303522</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303523" alias="SHAH_H000340_T03_03_DLP01-128689A-R23-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303523</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303524</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303525</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303526</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303527</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303528" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303528</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303529" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303529</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303530" alias="SHAH_H000340_T03_03_DLP01-128689A-R24-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303530</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R24-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303531" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303531</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303532" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303532</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303533</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303534</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <PRIMARY_ID>SRX23303535</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303536</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303537" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303537</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303538" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303538</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303539" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303539</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303540" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303540</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303541" alias="SHAH_H000340_T03_03_DLP01-128689A-R25-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303541</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R25-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303542</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303543</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303544</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303545</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303546" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303546</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303547" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303547</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303548" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303548</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303549" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303549</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303550" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303550</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303551</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303552</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303553</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303554</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303555" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303555</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303556" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303556</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303557" alias="SHAH_H000340_T03_03_DLP01-128689A-R26-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303557</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R26-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R26-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303558" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303558</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303559" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303559</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C16</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303560</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303561</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303562</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303563</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303564" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303564</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303565" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303565</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303566" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303566</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303567" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303567</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303568" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303568</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303569</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303570</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303571</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303572</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303573" alias="SHAH_H000340_T03_03_DLP01-128689A-R28-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303573</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R28-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R28-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303574" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303574</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303575" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303575</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303576" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303576</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303577" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303577</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303578</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303579</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303580</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303581</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303582" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303582</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303583" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303583</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303584" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303584</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303585" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303585</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303586" alias="SHAH_H000340_T03_03_DLP01-128689A-R29-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303586</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R29-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R29-C62</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303587</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303588</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303589</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303590</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303591" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303591</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303592" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303592</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303593" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303593</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C44</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303594" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C45">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303594</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303595" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303595</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C46</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303596</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303597</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303598</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303599</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303600" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303600</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303601</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303602" alias="SHAH_H000340_T03_03_DLP01-128689A-R30-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303602</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R30-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303603</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303604</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R30-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303605</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303606</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303607</PRIMARY_ID>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303608</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303609" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303609</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303610" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C54">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303610</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C54</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303611" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C55">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303611</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303612" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303612</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303613" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303613</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C57</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303614</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303615</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303616</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C60</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303617</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303618" alias="SHAH_H000340_T03_03_DLP01-128689A-R31-C62">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303618</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R31-C62</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R31-C62</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303619" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303619</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303620" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303620</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303621" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303621</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303622" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303622</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C31</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303623</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303624</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C43</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303625</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303626</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303627" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303627</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303628" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303628</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303629" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303629</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303630" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303630</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303631" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303631</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C50</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303632</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303633</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303634</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303635</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C55</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303636" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C56">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303636</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C56</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303637" alias="SHAH_H000340_T03_03_DLP01-128689A-R32-C57">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303637</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R32-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R32-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303638" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303638</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303639" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303639</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303640" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303640</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303641</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C26</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303642</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303643</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303644</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303645" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303645</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303646" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303646</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C31</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303647" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303647</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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  <EXPERIMENT accession="SRX23303648" alias="SHAH_H000340_T03_03_DLP01-128689A-R42-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303648</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C43</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303649</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303650</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303651</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303652</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303653</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R42-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R42-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303654" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303654</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303655" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303655</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303656" alias="SHAH_H000340_T03_03_DLP01-128689A-R43-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303656</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R43-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R43-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303657" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303657</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303658" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303658</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303659</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303660</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303662</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303663" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303663</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303664" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303664</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303665" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303665</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303666" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303666</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303667" alias="SHAH_H000340_T03_03_DLP01-128689A-R44-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303667</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R44-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303668</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303669</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R44-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303670</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303671</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303672" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303672</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303673" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303673</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303674" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303674</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303675" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303675</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303676" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303676</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303677</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    </DESIGN>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303678</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303679</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303680</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303681" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303681</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303682" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303682</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303683" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303683</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303684" alias="SHAH_H000340_T03_03_DLP01-128689A-R45-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303684</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303685</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R45-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R45-C43</LIBRARY_NAME>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303686</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303687</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303688</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303689</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303690" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303690</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303691" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303691</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303692" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303692</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303693" alias="SHAH_H000340_T03_03_DLP01-128689A-R46-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303693</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R46-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R46-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303694" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303694</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303695</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303696</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303697</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303698</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303699" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303699</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303700" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303700</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303701" alias="SHAH_H000340_T03_03_DLP01-128689A-R47-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303701</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R47-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R47-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303702" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303702</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303703" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303703</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303704</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303705</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303706</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303707</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303708" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303708</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303709" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303709</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303710" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303710</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303711" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303711</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303712" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303712</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303713" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303713</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C24</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303714</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C25</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303715</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C26</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303716</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303717" alias="SHAH_H000340_T03_03_DLP01-128689A-R48-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303717</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R48-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R48-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303718" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303718</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303719" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303719</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303720" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C24">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303720</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303721" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303721</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303722</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303723</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C27</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303724</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C28</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303725</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303726" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303726</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303727" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303727</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303728" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303728</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303729" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303729</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303730" alias="SHAH_H000340_T03_03_DLP01-128689A-R49-C44">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303730</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R49-C44</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303731</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303732</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R49-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303733</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303734</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303735" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303735</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303736" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303736</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303737" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303737</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303738" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303738</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303739" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303739</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303740" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303740</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303741</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303742</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303743</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303744" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303744</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303745" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303745</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303746" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303746</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303747" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303747</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303748" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303748</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303749</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303750</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303751</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303752</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303753" alias="SHAH_H000340_T03_03_DLP01-128689A-R50-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303753</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R50-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R50-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303754" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303754</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303755" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303755</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303756" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303756</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303757" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C15">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303757</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303758</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303759</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303760</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303761</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303762" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303762</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303763" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303763</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303764" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C22">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303764</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303765" alias="SHAH_H000340_T03_03_DLP01-128689A-R51-C23">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303765</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R51-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R51-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303766" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C43">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303766</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C43</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303767</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303768</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303769</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303770</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303771" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303771</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303772" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303772</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303773" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303773</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303774" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303774</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303775" alias="SHAH_H000340_T03_03_DLP01-128689A-R52-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303775</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303776</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303777</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303778</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303779</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303780</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C58</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303781</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R52-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R52-C59</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303782</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C52</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303783</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303784</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303785</PRIMARY_ID>
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    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303786</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303788</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303789" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303789</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303790" alias="SHAH_H000340_T03_03_DLP01-128689A-R53-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303790</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R53-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R53-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303791" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303791</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303792" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C13">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303792</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C13</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303793" alias="SHAH_H000340_T03_03_DLP01-128689A-R54-C14">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303793</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C14</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303794</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303795</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303796</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303797</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R54-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R54-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303798" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303798</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303799" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303799</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303800" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303800</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303801" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303801</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303802" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C42">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303802</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C42</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303803</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303804</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
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        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303805</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C45</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C45</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303806</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303807" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303807</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303808" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303808</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303809" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C49">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303809</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C49</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C49</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303810" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C50">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303810</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C50</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C50</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303811" alias="SHAH_H000340_T03_03_DLP01-128689A-R55-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303811</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R55-C51</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303812</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303813</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R55-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303814</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C14</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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          <PAIRED/>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303815</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C15</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303816" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C16">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303816</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303817" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303817</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303818" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C18">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303818</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C18</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C18</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303819" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C19">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303819</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C19</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C19</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303820" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C20">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303820</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C20</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C20</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303821" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C21">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303821</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C21</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C21</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303822</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C22</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C22</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303823</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C23</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303824</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C24</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303825" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C25">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303825</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C25</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C25</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303826" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C26">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303826</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303827" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303827</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303828" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303828</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303829" alias="SHAH_H000340_T03_03_DLP01-128689A-R57-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303829</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R57-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R57-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303830</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C23</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303831</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C24</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303832</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C25</SUBMITTER_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303833</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C26</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C26</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303834" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C27">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303834</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C27</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C27</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303835" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C28">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303835</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C28</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C28</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303836" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C29">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303836</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C29</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C29</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303837" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C30">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303837</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C30</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C30</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303838" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C31">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303838</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C31</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C31</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303839</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C42</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303840</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C43</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C43</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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        <TAG>alignment_software</TAG>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303841</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C44</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C44</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303842</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C45</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C45</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303843" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C46">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303843</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C46</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C46</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303844" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C47">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303844</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C47</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C47</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303845" alias="SHAH_H000340_T03_03_DLP01-128689A-R58-C48">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303845</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R58-C48</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R58-C48</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303846" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C51">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303846</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C51</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C51</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303847" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C52">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303847</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C52</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C52</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303848</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C54</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C54</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303849</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C55</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
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    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C55</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303850</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C56</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        </IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C56</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303851</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C57</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C57</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303852" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C58">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303852</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C58</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C58</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303853" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C59">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303853</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C59</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C59</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303854" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C60">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303854</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C60</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C60</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303855" alias="SHAH_H000340_T03_03_DLP01-128689A-R60-C61">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303855</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R60-C61</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R60-C61</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303856" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C12">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303856</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C12</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C12</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303857</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C13</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        </IDENTIFIERS>
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        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303858</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C14</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C14</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    </EXPERIMENT_ATTRIBUTES>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303859</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C15</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303860</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C16</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
        <EXTERNAL_ID namespace="dbGaP">phs002857</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
          <SUBMITTER_ID namespace="phs002857">SHAH_H000340_T03_03_DLP01</SUBMITTER_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C16</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303861" alias="SHAH_H000340_T03_03_DLP01-128689A-R61-C17">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303861</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R61-C17</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R61-C17</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303862" alias="SHAH_H000340_T03_03_DLP01-128689A-R13-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303862</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R13-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R13-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303863" alias="SHAH_H000340_T03_03_DLP01-128689A-R14-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303863</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R14-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
    <STUDY_REF accession="SRP403980">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS20180831" refname="SHAH_H000340_T03_03_DLP01" refcenter="phs002857">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R14-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303864" alias="SHAH_H000340_T03_03_DLP01-128689A-R15-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303864</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R15-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R15-C03</LIBRARY_NAME>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303865" alias="SHAH_H000340_T03_03_DLP01-128689A-R16-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303865</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R16-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R16-C03</LIBRARY_NAME>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303866</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R17-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303867</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R18-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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    <IDENTIFIERS>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303869</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R20-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R20-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX23303870" alias="SHAH_H000340_T03_03_DLP01-128689A-R21-C03">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303870</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R21-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R21-C03</LIBRARY_NAME>
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        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_ATTRIBUTES>
      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
      </EXPERIMENT_ATTRIBUTE>
    </EXPERIMENT_ATTRIBUTES>
  </EXPERIMENT>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303871</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R22-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R22-C03</LIBRARY_NAME>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303872</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R23-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <IDENTIFIERS>
          <PRIMARY_ID>SRS20180831</PRIMARY_ID>
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      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>SHAH_H000340_T03_03_DLP01-128689A-R23-C03</LIBRARY_NAME>
        <LIBRARY_STRATEGY>WGS</LIBRARY_STRATEGY>
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        <LIBRARY_SELECTION>RANDOM</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303873</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R24-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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        <PRIMARY_ID>SRP403980</PRIMARY_ID>
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      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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        <INSTRUMENT_MODEL>Illumina NovaSeq 6000</INSTRUMENT_MODEL>
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      <EXPERIMENT_ATTRIBUTE>
        <TAG>alignment_software</TAG>
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    <IDENTIFIERS>
      <PRIMARY_ID>SRX23303874</PRIMARY_ID>
      <SUBMITTER_ID namespace="NIH-phs002857">SHAH_H000340_T03_03_DLP01-128689A-R25-C03</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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      <IDENTIFIERS>
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    <DESIGN>
      <DESIGN_DESCRIPTION>scWGS libraries were prepared using the DLP+ protocol.  In brief, single cell suspensions were fluorescently stained with a combination of CellTrace CFSE Cell Proliferation Kit (ThermoFisher) and LIVE/DEAD Fixable Red Dead Cell Stains. Cells were dispensed into a 72x72 open nanowell array (TakaraBio SmartChip) using a cell dispensing system that combines a contactless piezoacoustic dispenser with brightfield and fluorescent imaging to select live cells and exclude doublets (cellenONE, Scienion). Isolated cells (target 800-1600 per sample) were be subjected to cell lysis, Tn5 based tagmentation to fragment DNA and incorporate illumine adapters, PCR to incorporate cell specific barcodes, and subsequently pooled and illumina sequenced on the Novaseq 6000 with 2x150bp reads to ~0.05X per cell coverage.</DESIGN_DESCRIPTION>
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      <PRIMARY_ID>SRX23303875</PRIMARY_ID>
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    <TITLE>Single cellwhole genome sequencing of tumor sample from high-grade serous ovarian cancer patient.: Sample SHAH_H000340_T03_03_DLP01</TITLE>
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